MIA40_ORYSJ
ID MIA40_ORYSJ Reviewed; 151 AA.
AC Q7XKI7;
DT 02-NOV-2016, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2004, sequence version 2.
DT 03-AUG-2022, entry version 112.
DE RecName: Full=Mitochondrial intermembrane space import and assembly protein 40 homolog {ECO:0000305};
DE Short=OsMIA40 {ECO:0000303|PubMed:20829360};
GN Name=MIA40 {ECO:0000303|PubMed:20829360};
GN OrderedLocusNames=Os04g0527700 {ECO:0000312|EMBL:BAS90175.1},
GN LOC_Os04g44550 {ECO:0000305};
GN ORFNames=OsJ_15538 {ECO:0000312|EMBL:EEE61375.1},
GN OSJNBa0038O10.21 {ECO:0000312|EMBL:CAE05655.2};
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12447439; DOI=10.1038/nature01183;
RA Feng Q., Zhang Y., Hao P., Wang S., Fu G., Huang Y., Li Y., Zhu J., Liu Y.,
RA Hu X., Jia P., Zhang Y., Zhao Q., Ying K., Yu S., Tang Y., Weng Q.,
RA Zhang L., Lu Y., Mu J., Lu Y., Zhang L.S., Yu Z., Fan D., Liu X., Lu T.,
RA Li C., Wu Y., Sun T., Lei H., Li T., Hu H., Guan J., Wu M., Zhang R.,
RA Zhou B., Chen Z., Chen L., Jin Z., Wang R., Yin H., Cai Z., Ren S., Lv G.,
RA Gu W., Zhu G., Tu Y., Jia J., Zhang Y., Chen J., Kang H., Chen X., Shao C.,
RA Sun Y., Hu Q., Zhang X., Zhang W., Wang L., Ding C., Sheng H., Gu J.,
RA Chen S., Ni L., Zhu F., Chen W., Lan L., Lai Y., Cheng Z., Gu M., Jiang J.,
RA Li J., Hong G., Xue Y., Han B.;
RT "Sequence and analysis of rice chromosome 4.";
RL Nature 420:316-320(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=15685292; DOI=10.1371/journal.pbio.0030038;
RA Yu J., Wang J., Lin W., Li S., Li H., Zhou J., Ni P., Dong W., Hu S.,
RA Zeng C., Zhang J., Zhang Y., Li R., Xu Z., Li S., Li X., Zheng H., Cong L.,
RA Lin L., Yin J., Geng J., Li G., Shi J., Liu J., Lv H., Li J., Wang J.,
RA Deng Y., Ran L., Shi X., Wang X., Wu Q., Li C., Ren X., Wang J., Wang X.,
RA Li D., Liu D., Zhang X., Ji Z., Zhao W., Sun Y., Zhang Z., Bao J., Han Y.,
RA Dong L., Ji J., Chen P., Wu S., Liu J., Xiao Y., Bu D., Tan J., Yang L.,
RA Ye C., Zhang J., Xu J., Zhou Y., Yu Y., Zhang B., Zhuang S., Wei H.,
RA Liu B., Lei M., Yu H., Li Y., Xu H., Wei S., He X., Fang L., Zhang Z.,
RA Zhang Y., Huang X., Su Z., Tong W., Li J., Tong Z., Li S., Ye J., Wang L.,
RA Fang L., Lei T., Chen C.-S., Chen H.-C., Xu Z., Li H., Huang H., Zhang F.,
RA Xu H., Li N., Zhao C., Li S., Dong L., Huang Y., Li L., Xi Y., Qi Q.,
RA Li W., Zhang B., Hu W., Zhang Y., Tian X., Jiao Y., Liang X., Jin J.,
RA Gao L., Zheng W., Hao B., Liu S.-M., Wang W., Yuan L., Cao M.,
RA McDermott J., Samudrala R., Wang J., Wong G.K.-S., Yang H.;
RT "The genomes of Oryza sativa: a history of duplications.";
RL PLoS Biol. 3:266-281(2005).
RN [6]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [7]
RP SUBCELLULAR LOCATION.
RX PubMed=20829360; DOI=10.1074/jbc.m110.121202;
RA Carrie C., Giraud E., Duncan O., Xu L., Wang Y., Huang S., Clifton R.,
RA Murcha M., Filipovska A., Rackham O., Vrielink A., Whelan J.;
RT "Conserved and novel functions for Arabidopsis thaliana MIA40 in assembly
RT of proteins in mitochondria and peroxisomes.";
RL J. Biol. Chem. 285:36138-36148(2010).
CC -!- FUNCTION: Required for the import and folding of small cysteine-
CC containing proteins in the mitochondrial intermembrane space.
CC {ECO:0000305}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion intermembrane space
CC {ECO:0000305|PubMed:20829360}. Peroxisome matrix
CC {ECO:0000305|PubMed:20829360}.
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DR EMBL; AL663019; CAE05655.2; -; Genomic_DNA.
DR EMBL; AP008210; BAF15283.1; -; Genomic_DNA.
DR EMBL; AP014960; BAS90175.1; -; Genomic_DNA.
DR EMBL; CM000141; EEE61375.1; -; Genomic_DNA.
DR EMBL; AK072980; BAG93231.1; -; mRNA.
DR RefSeq; XP_015636074.1; XM_015780588.1.
DR AlphaFoldDB; Q7XKI7; -.
DR SMR; Q7XKI7; -.
DR STRING; 4530.OS04T0527700-01; -.
DR PaxDb; Q7XKI7; -.
DR PRIDE; Q7XKI7; -.
DR EnsemblPlants; Os04t0527700-01; Os04t0527700-01; Os04g0527700.
DR GeneID; 4336462; -.
DR Gramene; Os04t0527700-01; Os04t0527700-01; Os04g0527700.
DR KEGG; osa:4336462; -.
DR eggNOG; KOG4149; Eukaryota.
DR HOGENOM; CLU_120204_0_0_1; -.
DR InParanoid; Q7XKI7; -.
DR OMA; IRERCGX; -.
DR OrthoDB; 1594252at2759; -.
DR Proteomes; UP000000763; Chromosome 4.
DR Proteomes; UP000007752; Chromosome 4.
DR Proteomes; UP000059680; Chromosome 4.
DR GO; GO:0005758; C:mitochondrial intermembrane space; IBA:GO_Central.
DR GO; GO:0005782; C:peroxisomal matrix; IEA:UniProtKB-SubCell.
DR GO; GO:0015035; F:protein-disulfide reductase activity; IBA:GO_Central.
DR GO; GO:0045041; P:protein import into mitochondrial intermembrane space; IBA:GO_Central.
DR GO; GO:0022417; P:protein maturation by protein folding; IBA:GO_Central.
DR GO; GO:0006625; P:protein targeting to peroxisome; IEA:EnsemblPlants.
DR InterPro; IPR039289; CHCHD4.
DR PANTHER; PTHR21622; PTHR21622; 1.
PE 2: Evidence at transcript level;
KW Disulfide bond; Mitochondrion; Oxidoreductase; Peroxisome;
KW Protein transport; Redox-active center; Reference proteome; Translocation;
KW Transport.
FT CHAIN 1..151
FT /note="Mitochondrial intermembrane space import and
FT assembly protein 40 homolog"
FT /id="PRO_0000437985"
FT DOMAIN 73..117
FT /note="CHCH"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT REGION 1..35
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 123..151
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOTIF 76..86
FT /note="Cx9C motif 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT MOTIF 99..109
FT /note="Cx9C motif 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 65..67
FT /note="Redox-active"
FT /evidence="ECO:0000250|UniProtKB:Q8N4Q1"
FT DISULFID 76..109
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
FT DISULFID 86..99
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01150"
SQ SEQUENCE 151 AA; 16099 MW; 3995E5CF47B08FB7 CRC64;
MGQGLSQPAQ AVEEPSPPAV EAAPSSSPSP APAPSSLEAL AAEAMSFDED GNESIDVKVQ
KALDCPCVAE LKNGPCGSQF VDAFSCFLKS TEEEKGSDCV KPFIALQDCI KINPEAFSKE
ILEEEENDEE AEKSNLKVRA PAWSRESKPK L
