ID   MIC19_SCHPO             Reviewed;         162 AA.
AC   P87150;
DT   15-JUL-1998, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=MICOS complex subunit mic19;
GN   Name=mic19; ORFNames=SPBC25H2.09;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Component of the MICOS complex, a large protein complex of
CC       the mitochondrial inner membrane that plays crucial roles in the
CC       maintenance of crista junctions, inner membrane architecture, and
CC       formation of contact sites to the outer membrane. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the mitochondrial contact site and cristae
CC       organizing system (MICOS) complex. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Intermembrane side
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MICOS complex subunit Mic19 family.
CC       {ECO:0000305}.
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DR   EMBL; CU329671; CAB08785.1; -; Genomic_DNA.
DR   PIR; T40004; T40004.
DR   RefSeq; NP_596357.1; NM_001022278.2.
DR   AlphaFoldDB; P87150; -.
DR   SMR; P87150; -.
DR   BioGRID; 277090; 12.
DR   IntAct; P87150; 1.
DR   STRING; 4896.SPBC25H2.09.1; -.
DR   MaxQB; P87150; -.
DR   PaxDb; P87150; -.
DR   EnsemblFungi; SPBC25H2.09.1; SPBC25H2.09.1:pep; SPBC25H2.09.
DR   GeneID; 2540563; -.
DR   KEGG; spo:SPBC25H2.09; -.
DR   PomBase; SPBC25H2.09; mic19.
DR   VEuPathDB; FungiDB:SPBC25H2.09; -.
DR   eggNOG; ENOG502SDJV; Eukaryota.
DR   HOGENOM; CLU_1644699_0_0_1; -.
DR   InParanoid; P87150; -.
DR   OMA; GKSLNCW; -.
DR   PhylomeDB; P87150; -.
DR   PRO; PR:P87150; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0061617; C:MICOS complex; ISO:PomBase.
DR   GO; GO:0044284; C:mitochondrial crista junction; ISO:PomBase.
DR   GO; GO:0042407; P:cristae formation; ISO:PomBase.
DR   InterPro; IPR012471; DUF1690.
DR   Pfam; PF07956; DUF1690; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome.
FT   CHAIN           1..162
FT                   /note="MICOS complex subunit mic19"
FT                   /id="PRO_0000116491"
SQ   SEQUENCE   162 AA;  18767 MW;  E6553AEDCCAE9FA5 CRC64;
     MGNQQSQPEF VLRAPTEFSE KFVRHLQEST ETDTSRYMDM ENYIQKRVQD ELKQLQLRQK
     KAIDAIQEEE WKSNAKTIKD SQGSLDSNLL SAEFRSFQEK LEKQSSINDK ELKIKLKEVE
     SIRSDLLKCM SEHPDKSLIC HPLAEKFAIL ASKLHNPKVG SV