ID   MIMD_MYCS2              Reviewed;         114 AA.
AC   A0QTV0; I7G5F2;
DT   31-JAN-2018, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Propane 2-monooxygenase, effector component {ECO:0000303|PubMed:21183637};
DE   AltName: Full=Propane 2-monooxygenase, coupling protein component {ECO:0000303|PubMed:21183637};
GN   Name=mimD {ECO:0000303|PubMed:21183637};
GN   OrderedLocusNames=MSMEG_1974 {ECO:0000312|EMBL:ABK73591.1},
GN   MSMEI_1930 {ECO:0000312|EMBL:AFP38401.1};
OS   Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium
OS   smegmatis).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycolicibacterium.
OX   NCBI_TaxID=246196;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155 {ECO:0000312|Proteomes:UP000000757};
RA   Fleischmann R.D., Dodson R.J., Haft D.H., Merkel J.S., Nelson W.C.,
RA   Fraser C.M.;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155 {ECO:0000312|Proteomes:UP000006158};
RX   PubMed=17295914; DOI=10.1186/gb-2007-8-2-r20;
RA   Deshayes C., Perrodou E., Gallien S., Euphrasie D., Schaeffer C.,
RA   Van-Dorsselaer A., Poch O., Lecompte O., Reyrat J.-M.;
RT   "Interrupted coding sequences in Mycobacterium smegmatis: authentic
RT   mutations or sequencing errors?";
RL   Genome Biol. 8:R20.1-R20.9(2007).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700084 / mc(2)155 {ECO:0000312|Proteomes:UP000006158};
RX   PubMed=18955433; DOI=10.1101/gr.081901.108;
RA   Gallien S., Perrodou E., Carapito C., Deshayes C., Reyrat J.-M.,
RA   Van Dorsselaer A., Poch O., Schaeffer C., Lecompte O.;
RT   "Ortho-proteogenomics: multiple proteomes investigation through orthology
RT   and a new MS-based protocol.";
RL   Genome Res. 19:128-135(2009).
RN   [4]
RP   FUNCTION, INDUCTION BY ACETONE, AND SUBUNIT.
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=21183637; DOI=10.1128/aem.02316-10;
RA   Furuya T., Hirose S., Osanai H., Semba H., Kino K.;
RT   "Identification of the monooxygenase gene clusters responsible for the
RT   regioselective oxidation of phenol to hydroquinone in mycobacteria.";
RL   Appl. Environ. Microbiol. 77:1214-1220(2011).
RN   [5]
RP   INDUCTION BY MIMR.
RC   STRAIN=ATCC 700084 / mc(2)155;
RX   PubMed=21856847; DOI=10.1128/jb.05525-11;
RA   Furuya T., Hirose S., Semba H., Kino K.;
RT   "Identification of the regulator gene responsible for the acetone-
RT   responsive expression of the binuclear iron monooxygenase gene cluster in
RT   mycobacteria.";
RL   J. Bacteriol. 193:5817-5823(2011).
CC   -!- FUNCTION: Effector component of the propane 2-monooxygenase
CC       multicomponent enzyme system which is involved in the degradation of
CC       propane via the O2-dependent hydroxylation of propane.
CC       {ECO:0000269|PubMed:21183637}.
CC   -!- SUBUNIT: The propane 2-monooxygenase multicomponent enzyme system is
CC       composed of an electron transfer component and a monooxygenase
CC       component interacting with the effector protein MimD. The electron
CC       transfer component is composed of a reductase (MimB), and the
CC       monooxygenase component is formed by a large subunit (MimA) and a small
CC       subunit (MimC). {ECO:0000305|PubMed:21183637}.
CC   -!- INDUCTION: By acetone (PubMed:21183637). Transcriptionally activated by
CC       MimR (PubMed:21856847). {ECO:0000269|PubMed:21183637,
CC       ECO:0000269|PubMed:21856847}.
CC   -!- SIMILARITY: Belongs to the TmoD/XamoD family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AFP38401.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; CP000480; ABK73591.1; -; Genomic_DNA.
DR   EMBL; CP001663; AFP38401.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_003893349.1; NZ_SIJM01000020.1.
DR   RefSeq; YP_886338.1; NC_008596.1.
DR   AlphaFoldDB; A0QTV0; -.
DR   SMR; A0QTV0; -.
DR   STRING; 246196.MSMEI_1930; -.
DR   EnsemblBacteria; ABK73591; ABK73591; MSMEG_1974.
DR   EnsemblBacteria; AFP38401; AFP38401; MSMEI_1930.
DR   GeneID; 66733404; -.
DR   KEGG; msg:MSMEI_1930; -.
DR   KEGG; msm:MSMEG_1974; -.
DR   PATRIC; fig|246196.19.peg.1951; -.
DR   eggNOG; ENOG5032SNE; Bacteria.
DR   OMA; PAMIRID; -.
DR   OrthoDB; 1687903at2; -.
DR   Proteomes; UP000000757; Chromosome.
DR   Proteomes; UP000006158; Chromosome.
DR   GO; GO:0004497; F:monooxygenase activity; IEA:InterPro.
DR   GO; GO:0006725; P:cellular aromatic compound metabolic process; IEA:InterPro.
DR   Gene3D; 3.90.56.10; -; 1.
DR   InterPro; IPR003454; MOase_MmoB_DmpM.
DR   InterPro; IPR036889; mOase_MmoB_DmpM_sf.
DR   Pfam; PF02406; MmoB_DmpM; 1.
DR   SUPFAM; SSF56029; SSF56029; 1.
PE   1: Evidence at protein level;
KW   Reference proteome.
FT   CHAIN           1..114
FT                   /note="Propane 2-monooxygenase, effector component"
FT                   /id="PRO_0000442975"
SQ   SEQUENCE   114 AA;  12533 MW;  F99CC94A43659803 CRC64;
     MSSMQFGAAT EFSNKCGVTL MNTPIGRVVA EVMGAKEGVE LTEYPSMIRV DGVKLLSFDY
     DELTEALGEE FDGSIFEEIS STHYGRMVHL DDKTMLFASP EDAAEYIGFD LTAK