ID   MIMR_MYCGD              Reviewed;         583 AA.
AC   G3XGC1;
DT   31-JAN-2018, integrated into UniProtKB/Swiss-Prot.
DT   14-DEC-2011, sequence version 1.
DT   03-AUG-2022, entry version 42.
DE   RecName: Full=Propane 2-monooxygenase operon transcriptional activator MimR {ECO:0000303|Ref.1};
GN   Name=mimR {ECO:0000303|Ref.1};
OS   Mycobacterium goodii (Mycolicibacterium goodii).
OC   Bacteria; Actinobacteria; Corynebacteriales; Mycobacteriaceae;
OC   Mycobacterium.
OX   NCBI_TaxID=134601;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
RC   STRAIN=12523 {ECO:0000312|EMBL:BAL03068.1};
RA   Furuya T., Hirose S., Semba H., Kino K.;
RT   "Identification of the regulator gene responsible for the acetone-
RT   responsive expression of the binuclear iron monooxygenase gene cluster in
RT   Mycobacteria.";
RL   J. Bacteriol. 193:5817-5823(2011).
CC   -!- FUNCTION: Acts as a transcriptional activator of the mimABCD operon
CC       encoding the propane 2-monooxygenase complex. {ECO:0000269|Ref.1}.
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DR   EMBL; AB627360; BAL03068.1; -; Genomic_DNA.
DR   AlphaFoldDB; G3XGC1; -.
DR   SMR; G3XGC1; -.
DR   STRING; 134601.AFA91_29125; -.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:InterPro.
DR   Gene3D; 3.30.450.40; -; 1.
DR   InterPro; IPR003018; GAF.
DR   InterPro; IPR029016; GAF-like_dom_sf.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR002197; HTH_Fis.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR002078; Sigma_54_int.
DR   Pfam; PF01590; GAF; 1.
DR   Pfam; PF02954; HTH_8; 1.
DR   PRINTS; PR01590; HTHFIS.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   PROSITE; PS50045; SIGMA54_INTERACT_4; 1.
PE   4: Predicted;
KW   Activator; ATP-binding; DNA-binding; Nucleotide-binding; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..583
FT                   /note="Propane 2-monooxygenase operon transcriptional
FT                   activator MimR"
FT                   /id="PRO_0000442977"
FT   DOMAIN          320..513
FT                   /note="Sigma-54 factor interaction"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   BINDING         348..355
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
FT   BINDING         395..404
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00193"
SQ   SEQUENCE   583 AA;  64013 MW;  54CCA19C6F1BF399 CRC64;
     MVRPADSSVD AQRAREQFLS AGALQPDAVA PSVLNSWQRS RELQVHPDRV DLPYLRDPDT
     DTPLMHAAAP VLRRIAEDLS DQAVSVVLTS ADGLVLDRIA ADTEFERILD DVRLARGYSY
     AEEFAGTNGI GTALETGQPA FIRGSEHYVG TLGGLACAGS PIREPVTRRI LGVVDLTCWA
     RQADPLLFVL AKSAGSQIED RLRTMNNETE TALLDAYLKQ SRRYPGGVLA IGGDVVLMNR
     YLRQALDAAD QTVLLDHAAE LTRSSFTSTT VAQLPSGASV KISAAERIMV GVRGDSVVLH
     VSVHVAESIP VRGSQHIPRL AGRSSSFRRS AHQVERCYRD REWVVIEGEK GSGRTHLGYS
     VARFVTPEKT IPVLRIGDFE TPESFVAAFD SETDDADFAV IVADVDELPD EVLHPLAAVM
     QTRAGRGWIA ATTSAERDSQ LVDMLMLPFF IHTVTVPALR HRIEDLHELV PMLLNELSRG
     EARMDAEAMR QLAKLPWPGN IAQLRHVLTE TLRRQRSGVI GADKLPSECR SVTRRKLTRL
     EAMERDAIVR SLLENDGNKA EAAEALGMSR ATIYRKIKDF GIA