MINC_AGRFC
ID MINC_AGRFC Reviewed; 242 AA.
AC Q8UAW8;
DT 01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-2002, sequence version 2.
DT 25-MAY-2022, entry version 103.
DE RecName: Full=Probable septum site-determining protein MinC {ECO:0000255|HAMAP-Rule:MF_00267};
GN Name=minC {ECO:0000255|HAMAP-Rule:MF_00267}; OrderedLocusNames=Atu3249;
GN ORFNames=AGR_L_3131;
OS Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens
OS (strain C58)).
OC Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC Rhizobiaceae; Rhizobium/Agrobacterium group; Agrobacterium;
OC Agrobacterium tumefaciens complex.
OX NCBI_TaxID=176299;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970;
RX PubMed=11743193; DOI=10.1126/science.1066804;
RA Wood D.W., Setubal J.C., Kaul R., Monks D.E., Kitajima J.P., Okura V.K.,
RA Zhou Y., Chen L., Wood G.E., Almeida N.F. Jr., Woo L., Chen Y.,
RA Paulsen I.T., Eisen J.A., Karp P.D., Bovee D. Sr., Chapman P.,
RA Clendenning J., Deatherage G., Gillet W., Grant C., Kutyavin T., Levy R.,
RA Li M.-J., McClelland E., Palmieri A., Raymond C., Rouse G.,
RA Saenphimmachak C., Wu Z., Romero P., Gordon D., Zhang S., Yoo H., Tao Y.,
RA Biddle P., Jung M., Krespan W., Perry M., Gordon-Kamm B., Liao L., Kim S.,
RA Hendrick C., Zhao Z.-Y., Dolan M., Chumley F., Tingey S.V., Tomb J.-F.,
RA Gordon M.P., Olson M.V., Nester E.W.;
RT "The genome of the natural genetic engineer Agrobacterium tumefaciens
RT C58.";
RL Science 294:2317-2323(2001).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C58 / ATCC 33970;
RX PubMed=11743194; DOI=10.1126/science.1066803;
RA Goodner B., Hinkle G., Gattung S., Miller N., Blanchard M., Qurollo B.,
RA Goldman B.S., Cao Y., Askenazi M., Halling C., Mullin L., Houmiel K.,
RA Gordon J., Vaudin M., Iartchouk O., Epp A., Liu F., Wollam C., Allinger M.,
RA Doughty D., Scott C., Lappas C., Markelz B., Flanagan C., Crowell C.,
RA Gurson J., Lomo C., Sear C., Strub G., Cielo C., Slater S.;
RT "Genome sequence of the plant pathogen and biotechnology agent
RT Agrobacterium tumefaciens C58.";
RL Science 294:2323-2328(2001).
CC -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC ring septums. Rapidly oscillates between the poles of the cell to
CC destabilize FtsZ filaments that have formed before they mature into
CC polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAK90140.2; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AE007870; AAK90140.2; ALT_INIT; Genomic_DNA.
DR PIR; AC2956; AC2956.
DR PIR; B98327; B98327.
DR RefSeq; NP_357355.2; NC_003063.2.
DR RefSeq; WP_035257422.1; NC_003063.2.
DR AlphaFoldDB; Q8UAW8; -.
DR SMR; Q8UAW8; -.
DR STRING; 176299.Atu3249; -.
DR EnsemblBacteria; AAK90140; AAK90140; Atu3249.
DR GeneID; 66223561; -.
DR KEGG; atu:Atu3249; -.
DR PATRIC; fig|176299.10.peg.3091; -.
DR eggNOG; COG0850; Bacteria.
DR HOGENOM; CLU_067812_1_0_5; -.
DR OMA; IYKMAED; -.
DR Proteomes; UP000000813; Chromosome linear.
DR GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0051302; P:regulation of cell division; IEA:InterPro.
DR GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR Gene3D; 2.160.20.70; -; 1.
DR HAMAP; MF_00267; MinC; 1.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR013033; MinC.
DR InterPro; IPR036145; MinC_C_sf.
DR InterPro; IPR007874; MinC_N.
DR InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR PANTHER; PTHR34108; PTHR34108; 1.
DR Pfam; PF03775; MinC_C; 1.
DR Pfam; PF05209; MinC_N; 1.
DR SUPFAM; SSF63848; SSF63848; 1.
DR TIGRFAMs; TIGR01222; minC; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Reference proteome; Septation.
FT CHAIN 1..242
FT /note="Probable septum site-determining protein MinC"
FT /id="PRO_0000189011"
SQ SEQUENCE 242 AA; 25756 MW; 173AB5EE064B0BFD CRC64;
MTKVLTDQRS IRIKGRSFLA VVLSPESPVD QWLERLDDLA ARSAGFFLSR PVVLDVSELS
LDKAGLKELL AALRERNVGI MGIEGVRPSM IEPGMPPSLK GGKPASDVEV EPVAVAAELP
EDKPHASGEV RAVVQSLVIN EPVRSGQSIM FPEGDVTVIG SVASGAEIIA GGSVHIYGAL
RGRAMAGSLG NVSARIFCRK LEAELLAIDG VYKVAEDIDD KLRGQPVQLW LENDTIKAAK
LG