ID   MINC_BRUME              Reviewed;         248 AA.
AC   Q8YBH3;
DT   01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-2002, sequence version 2.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=Probable septum site-determining protein MinC {ECO:0000255|HAMAP-Rule:MF_00267};
GN   Name=minC {ECO:0000255|HAMAP-Rule:MF_00267}; OrderedLocusNames=BMEII0927;
OS   Brucella melitensis biotype 1 (strain 16M / ATCC 23456 / NCTC 10094).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=224914;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=16M / ATCC 23456 / NCTC 10094;
RX   PubMed=11756688; DOI=10.1073/pnas.221575398;
RA   DelVecchio V.G., Kapatral V., Redkar R.J., Patra G., Mujer C., Los T.,
RA   Ivanova N., Anderson I., Bhattacharyya A., Lykidis A., Reznik G.,
RA   Jablonski L., Larsen N., D'Souza M., Bernal A., Mazur M., Goltsman E.,
RA   Selkov E., Elzer P.H., Hagius S., O'Callaghan D., Letesson J.-J.,
RA   Haselkorn R., Kyrpides N.C., Overbeek R.;
RT   "The genome sequence of the facultative intracellular pathogen Brucella
RT   melitensis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:443-448(2002).
CC   -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC       ring septums. Rapidly oscillates between the poles of the cell to
CC       destabilize FtsZ filaments that have formed before they mature into
CC       polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAL54169.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE008918; AAL54169.1; ALT_INIT; Genomic_DNA.
DR   PIR; AF3625; AF3625.
DR   RefSeq; WP_002966269.1; NZ_GG703779.1.
DR   AlphaFoldDB; Q8YBH3; -.
DR   SMR; Q8YBH3; -.
DR   STRING; 224914.BMEII0927; -.
DR   EnsemblBacteria; AAL54169; AAL54169; BMEII0927.
DR   GeneID; 3827943; -.
DR   KEGG; bme:BMEII0927; -.
DR   PATRIC; fig|224914.52.peg.2435; -.
DR   eggNOG; COG0850; Bacteria.
DR   OMA; IYKMAED; -.
DR   Proteomes; UP000000419; Chromosome II.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR   Gene3D; 2.160.20.70; -; 1.
DR   HAMAP; MF_00267; MinC; 1.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR013033; MinC.
DR   InterPro; IPR036145; MinC_C_sf.
DR   InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR   PANTHER; PTHR34108; PTHR34108; 1.
DR   Pfam; PF03775; MinC_C; 1.
DR   SUPFAM; SSF63848; SSF63848; 1.
DR   TIGRFAMs; TIGR01222; minC; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Septation.
FT   CHAIN           1..248
FT                   /note="Probable septum site-determining protein MinC"
FT                   /id="PRO_0000189022"
FT   REGION          94..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   248 AA;  26589 MW;  0E5F1D613F3C1A91 CRC64;
     MNQVLTETRP IRLKGRSFLA MVLSPELPLD GWLERLDDLA RRSSGFFLGR PVVLDMENLA
     IERAQLVYLL QALNDRGVWI MGVEGARPSL LGPGMPPAMR GGQPAADFEA PAGEPQANPG
     APEPQISQAV RAPGHAVHAM PSMVITEPVR SGQSVYFPEG DVTIVGSVAS GAEVVAGGSI
     HIYGTLRGRA LAGTAGNTSA RIFCRKLEAE LVAIDGLYKT AEDLEPRFRG QAVQLWLDGD
     YMMIDTLS