ID   MINC_BRUSU              Reviewed;         248 AA.
AC   Q8FWX2; G0KC62;
DT   31-OCT-2003, integrated into UniProtKB/Swiss-Prot.
DT   31-OCT-2003, sequence version 2.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=Probable septum site-determining protein MinC {ECO:0000255|HAMAP-Rule:MF_00267};
GN   Name=minC {ECO:0000255|HAMAP-Rule:MF_00267};
GN   OrderedLocusNames=BRA0321, BS1330_II0318;
OS   Brucella suis biovar 1 (strain 1330).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Brucellaceae; Brucella/Ochrobactrum group; Brucella.
OX   NCBI_TaxID=204722;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1330;
RX   PubMed=12271122; DOI=10.1073/pnas.192319099;
RA   Paulsen I.T., Seshadri R., Nelson K.E., Eisen J.A., Heidelberg J.F.,
RA   Read T.D., Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J.,
RA   Daugherty S.C., DeBoy R.T., Durkin A.S., Kolonay J.F., Madupu R.,
RA   Nelson W.C., Ayodeji B., Kraul M., Shetty J., Malek J.A., Van Aken S.E.,
RA   Riedmuller S., Tettelin H., Gill S.R., White O., Salzberg S.L.,
RA   Hoover D.L., Lindler L.E., Halling S.M., Boyle S.M., Fraser C.M.;
RT   "The Brucella suis genome reveals fundamental similarities between animal
RT   and plant pathogens and symbionts.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:13148-13153(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1330;
RX   PubMed=22038969; DOI=10.1128/jb.06181-11;
RA   Tae H., Shallom S., Settlage R., Preston D., Adams L.G., Garner H.R.;
RT   "Revised genome sequence of Brucella suis 1330.";
RL   J. Bacteriol. 193:6410-6410(2011).
CC   -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC       ring septums. Rapidly oscillates between the poles of the cell to
CC       destabilize FtsZ filaments that have formed before they mature into
CC       polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAN33521.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=AEM19800.1; Type=Erroneous initiation; Note=Extended N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AE014292; AAN33521.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CP002998; AEM19800.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_004692436.1; NZ_KN046805.1.
DR   AlphaFoldDB; Q8FWX2; -.
DR   SMR; Q8FWX2; -.
DR   EnsemblBacteria; AEM19800; AEM19800; BS1330_II0318.
DR   GeneID; 45053381; -.
DR   GeneID; 55592020; -.
DR   KEGG; bms:BRA0321; -.
DR   KEGG; bsi:BS1330_II0318; -.
DR   PATRIC; fig|204722.21.peg.187; -.
DR   HOGENOM; CLU_067812_1_0_5; -.
DR   Proteomes; UP000007104; Chromosome II.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR   Gene3D; 2.160.20.70; -; 1.
DR   HAMAP; MF_00267; MinC; 1.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR013033; MinC.
DR   InterPro; IPR036145; MinC_C_sf.
DR   InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR   PANTHER; PTHR34108; PTHR34108; 1.
DR   Pfam; PF03775; MinC_C; 1.
DR   SUPFAM; SSF63848; SSF63848; 1.
DR   TIGRFAMs; TIGR01222; minC; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Septation.
FT   CHAIN           1..248
FT                   /note="Probable septum site-determining protein MinC"
FT                   /id="PRO_0000189023"
FT   REGION          94..126
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   248 AA;  26545 MW;  809EF17FFED5A570 CRC64;
     MNQVLTETRP IRLKGRSFLA MVLSPELPLD GWLELLDDLA RRSSGFFLGR PVVLDMENLA
     IERAQLVYLL QALNDRGVWI MGVEGARPSL LGPGMPPAMR GGQPAADFEA PAGEPQANPG
     APEPQISQAV RAPGHAVHAM PSMVITEPVR SGQSVYFPEG DVTIVGSVAS GAEVVAGGSI
     HIYGTLRGRA LAGTAGNTSA RIFCRKLEAE LVAIDGLYKT AEDLEPRFRG QAVQLWLDGD
     YMMIDTLS