ID   MINC_BURCJ              Reviewed;         261 AA.
AC   B4EBR1;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   23-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 78.
DE   RecName: Full=Probable septum site-determining protein MinC {ECO:0000255|HAMAP-Rule:MF_00267};
GN   Name=minC {ECO:0000255|HAMAP-Rule:MF_00267};
GN   OrderedLocusNames=BceJ2315_29730; ORFNames=BCAL3027;
OS   Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 16656 /
OS   NCTC 13227 / J2315 / CF5610) (Burkholderia cepacia (strain J2315)).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; Burkholderia cepacia complex.
OX   NCBI_TaxID=216591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC BAA-245 / DSM 16553 / LMG 16656 / NCTC 13227 / J2315 / CF5610;
RX   PubMed=18931103; DOI=10.1128/jb.01230-08;
RA   Holden M.T., Seth-Smith H.M., Crossman L.C., Sebaihia M., Bentley S.D.,
RA   Cerdeno-Tarraga A.M., Thomson N.R., Bason N., Quail M.A., Sharp S.,
RA   Cherevach I., Churcher C., Goodhead I., Hauser H., Holroyd N., Mungall K.,
RA   Scott P., Walker D., White B., Rose H., Iversen P., Mil-Homens D.,
RA   Rocha E.P., Fialho A.M., Baldwin A., Dowson C., Barrell B.G., Govan J.R.,
RA   Vandamme P., Hart C.A., Mahenthiralingam E., Parkhill J.;
RT   "The genome of Burkholderia cenocepacia J2315, an epidemic pathogen of
RT   cystic fibrosis patients.";
RL   J. Bacteriol. 191:261-277(2009).
CC   -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC       ring septums. Rapidly oscillates between the poles of the cell to
CC       destabilize FtsZ filaments that have formed before they mature into
CC       polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AM747720; CAR53349.1; -; Genomic_DNA.
DR   RefSeq; WP_006486623.1; NC_011000.1.
DR   AlphaFoldDB; B4EBR1; -.
DR   SMR; B4EBR1; -.
DR   STRING; 216591.BCAL3027; -.
DR   EnsemblBacteria; CAR53349; CAR53349; BCAL3027.
DR   KEGG; bcj:BCAL3027; -.
DR   eggNOG; COG0850; Bacteria.
DR   HOGENOM; CLU_067812_0_1_4; -.
DR   OMA; RRDPLWG; -.
DR   OrthoDB; 1665744at2; -.
DR   BioCyc; BCEN216591:G1G1V-3353-MON; -.
DR   Proteomes; UP000001035; Chromosome 1.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:0051302; P:regulation of cell division; IEA:InterPro.
DR   GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR   Gene3D; 2.160.20.70; -; 1.
DR   HAMAP; MF_00267; MinC; 1.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR013033; MinC.
DR   InterPro; IPR036145; MinC_C_sf.
DR   InterPro; IPR007874; MinC_N.
DR   InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR   PANTHER; PTHR34108; PTHR34108; 1.
DR   Pfam; PF03775; MinC_C; 1.
DR   Pfam; PF05209; MinC_N; 1.
DR   SUPFAM; SSF63848; SSF63848; 1.
DR   TIGRFAMs; TIGR01222; minC; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Septation.
FT   CHAIN           1..261
FT                   /note="Probable septum site-determining protein MinC"
FT                   /id="PRO_1000114271"
SQ   SEQUENCE   261 AA;  27978 MW;  0A603F4C317F45E2 CRC64;
     MSLKKSPFFE LRSGSVDTLL FTVKTTDLDA LRTELVKRFE ATPEFFADDV VAIDVRRLAD
     GERVALADIR QMLNDVRMRP VGVVALATQG WAGEAGLPLL EARDRRAPAA KPADEAEPAA
     VLAVEAAAAP AAAAAPEQSS DPVPTLLQAG GQTLVIDRPL RSGQQIYAKG DLVVLAPVSH
     GAEIIAEGNI HIYAPLRGRA LAGVHGNHDA RIFCTCLEPE LISIAGIYRT TENPLPADVL
     GKSVQIRLEE EKLMIEPLRL T