MINC_CLONN
ID MINC_CLONN Reviewed; 210 AA.
AC A0PZG9;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 09-JAN-2007, sequence version 1.
DT 25-MAY-2022, entry version 83.
DE RecName: Full=Probable septum site-determining protein MinC {ECO:0000255|HAMAP-Rule:MF_00267};
GN Name=minC {ECO:0000255|HAMAP-Rule:MF_00267}; OrderedLocusNames=NT01CX_1692;
OS Clostridium novyi (strain NT).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=386415;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NT;
RX PubMed=17115055; DOI=10.1038/nbt1256;
RA Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X.,
RA Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B.,
RA Zhou S.;
RT "The genome and transcriptomes of the anti-tumor agent Clostridium novyi-
RT NT.";
RL Nat. Biotechnol. 24:1573-1580(2006).
CC -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC ring septums. Rapidly oscillates between the poles of the cell to
CC destabilize FtsZ filaments that have formed before they mature into
CC polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
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DR EMBL; CP000382; ABK62026.1; -; Genomic_DNA.
DR RefSeq; WP_011721778.1; NC_008593.1.
DR AlphaFoldDB; A0PZG9; -.
DR SMR; A0PZG9; -.
DR STRING; 386415.NT01CX_1692; -.
DR DNASU; 4540157; -.
DR EnsemblBacteria; ABK62026; ABK62026; NT01CX_1692.
DR KEGG; cno:NT01CX_1692; -.
DR eggNOG; COG0850; Bacteria.
DR HOGENOM; CLU_048711_2_0_9; -.
DR OMA; EMECAYI; -.
DR OrthoDB; 1665744at2; -.
DR Proteomes; UP000008220; Chromosome.
DR GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR Gene3D; 2.160.20.70; -; 1.
DR HAMAP; MF_00267; MinC; 1.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR013033; MinC.
DR InterPro; IPR036145; MinC_C_sf.
DR InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR PANTHER; PTHR34108; PTHR34108; 1.
DR Pfam; PF03775; MinC_C; 1.
DR SUPFAM; SSF63848; SSF63848; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Reference proteome; Septation.
FT CHAIN 1..210
FT /note="Probable septum site-determining protein MinC"
FT /id="PRO_1000047822"
SQ SEQUENCE 210 AA; 23593 MW; 6CA8BA711EE42E4E CRC64;
MVRDSIVVKG NREGLNVIID MNKFQNFDEM LEIFIHKLSI GKKFYKGSTI IITTQLKEFN
EKQISKFEEV LFEDFLIKDC IFKDIRETKN KVFTGVYEGR TKFYRRTLRS GQVINYPGNI
VIVGDVNPGS EVYAGGNVIV IGNLCGEVHA GASGNTKAII AAFKLQPSIL QIANIMTRSP
EDGPKPSYPE VARIKDGIII VEPYLPNKFV