MINC_CLOPE
ID MINC_CLOPE Reviewed; 211 AA.
AC Q8XII0;
DT 01-NOV-2002, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2002, sequence version 1.
DT 25-MAY-2022, entry version 100.
DE RecName: Full=Probable septum site-determining protein MinC {ECO:0000255|HAMAP-Rule:MF_00267};
GN Name=minC {ECO:0000255|HAMAP-Rule:MF_00267}; OrderedLocusNames=CPE2139;
OS Clostridium perfringens (strain 13 / Type A).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC Clostridium.
OX NCBI_TaxID=195102;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=13 / Type A;
RX PubMed=11792842; DOI=10.1073/pnas.022493799;
RA Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T.,
RA Ogasawara N., Hattori M., Kuhara S., Hayashi H.;
RT "Complete genome sequence of Clostridium perfringens, an anaerobic flesh-
RT eater.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002).
CC -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC ring septums. Rapidly oscillates between the poles of the cell to
CC destabilize FtsZ filaments that have formed before they mature into
CC polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
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DR EMBL; BA000016; BAB81845.1; -; Genomic_DNA.
DR RefSeq; WP_003452463.1; NC_003366.1.
DR AlphaFoldDB; Q8XII0; -.
DR SMR; Q8XII0; -.
DR STRING; 195102.gene:10491409; -.
DR EnsemblBacteria; BAB81845; BAB81845; BAB81845.
DR GeneID; 29570498; -.
DR KEGG; cpe:CPE2139; -.
DR HOGENOM; CLU_048711_2_0_9; -.
DR OMA; EMECAYI; -.
DR Proteomes; UP000000818; Chromosome.
DR GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR Gene3D; 2.160.20.70; -; 1.
DR HAMAP; MF_00267; MinC; 1.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR013033; MinC.
DR InterPro; IPR036145; MinC_C_sf.
DR InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR PANTHER; PTHR34108; PTHR34108; 1.
DR Pfam; PF03775; MinC_C; 1.
DR SUPFAM; SSF63848; SSF63848; 1.
DR TIGRFAMs; TIGR01222; minC; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Reference proteome; Septation.
FT CHAIN 1..211
FT /note="Probable septum site-determining protein MinC"
FT /id="PRO_0000189030"
SQ SEQUENCE 211 AA; 23672 MW; 8CFE02C9CFAF511B CRC64;
MRDDRIFIKG NKLGINAIIN MDKFGNFDEM LDSLVEKLSR GKKFYKGATL TVTTDLKYIN
ERQISKLKDV LFDEILIKDC IFEERLEKQS SVFSGVYEGR TKFVRKTVRS GQCLNYAGNL
IIIGDVNNGG EVRAHGNVIV LGDLKGKVFA GDNGNENAII AAYSLEPELI SISGKITISP
DDFEKTGYPE VARLNENNII VEPYLPDKYS Y