ID   11S3_HELAN              Reviewed;         493 AA.
AC   P19084;
DT   01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1990, sequence version 1.
DT   25-MAY-2022, entry version 83.
DE   RecName: Full=11S globulin seed storage protein G3;
DE   AltName: Full=Helianthinin-G3;
DE   Contains:
DE     RecName: Full=11S globulin seed storage protein G3 acidic chain;
DE   Contains:
DE     RecName: Full=11S globulin seed storage protein G3 basic chain;
DE   Flags: Precursor;
GN   Name=HAG3;
OS   Helianthus annuus (Common sunflower).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   asterids; campanulids; Asterales; Asteraceae; Asteroideae;
OC   Heliantheae alliance; Heliantheae; Helianthus.
OX   NCBI_TaxID=4232;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2469623; DOI=10.1016/0378-1119(88)90176-x;
RA   Vonder Haar R.A., Allen R.D., Cohen E.A., Nessler C.L., Thomas T.L.;
RT   "Organization of the sunflower 11S storage protein gene family.";
RL   Gene 74:433-443(1988).
CC   -!- FUNCTION: This is a seed storage protein.
CC   -!- SUBUNIT: Hexamer; each subunit is composed of an acidic and a basic
CC       chain derived from a single precursor and linked by a disulfide bond.
CC   -!- SIMILARITY: Belongs to the 11S seed storage protein (globulins) family.
CC       {ECO:0000305}.
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DR   EMBL; M28832; AAA33374.1; -; Genomic_DNA.
DR   PIR; JA0089; JA0089.
DR   AlphaFoldDB; P19084; -.
DR   SMR; P19084; -.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   Gene3D; 2.60.120.10; -; 2.
DR   InterPro; IPR022379; 11S_seedstore_CS.
DR   InterPro; IPR006044; 11S_seedstore_pln.
DR   InterPro; IPR006045; Cupin_1.
DR   InterPro; IPR014710; RmlC-like_jellyroll.
DR   InterPro; IPR011051; RmlC_Cupin_sf.
DR   Pfam; PF00190; Cupin_1; 2.
DR   PRINTS; PR00439; 11SGLOBULIN.
DR   SMART; SM00835; Cupin_1; 2.
DR   SUPFAM; SSF51182; SSF51182; 1.
DR   PROSITE; PS00305; 11S_SEED_STORAGE; 1.
PE   3: Inferred from homology;
KW   Disulfide bond; Seed storage protein; Signal; Storage protein.
FT   SIGNAL          1..20
FT   CHAIN           21..305
FT                   /note="11S globulin seed storage protein G3 acidic chain"
FT                   /id="PRO_0000032025"
FT   CHAIN           306..493
FT                   /note="11S globulin seed storage protein G3 basic chain"
FT                   /id="PRO_0000032026"
FT   DOMAIN          37..248
FT                   /note="Cupin type-1 1"
FT                   /evidence="ECO:0000255"
FT   DOMAIN          318..467
FT                   /note="Cupin type-1 2"
FT                   /evidence="ECO:0000255"
FT   REGION          190..229
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          269..305
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        275..303
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   DISULFID        32..65
FT                   /evidence="ECO:0000250"
FT   DISULFID        103..312
FT                   /note="Interchain (between acidic and basic chains)"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   493 AA;  55687 MW;  A007B6F99D189AB5 CRC64;
     MASKATLLLA FTLLFATCIA RHQQRQQQQN QCQLQNIEAL EPIEVIQAEA GVTEIWDAYD
     QQFQCAWSIL FDTGFNLVAF SCLPTSTPLF WPSSREGVIL PGCRRTYEYS QEQQFSGEGG
     RRGGGEGTFR TVIRKLENLK EGDVVAIPTG TAHWLHNDGN TELVVVFLDT QNHENQLDEN
     QRRFFLAGNP QAQAQSQQQQ QRQPRQQSPQ RQRQRQRQGQ GQNAGNIFNG FTPELIAQSF
     NVDQETAQKL QGQNDQRGHI VNVGQDLQIV RPPQDRRSPR QQQEQATSPR QQQEQQQGRR
     GGWSNGVEET ICSMKFKVNI DNPSQADFVN PQAGSIANLN SFKFPILEHL RLSVERGELR
     PNAIQSPHWT INAHNLLYVT EGALRVQIVD NQGNSVFDNE LREGQVVVIP QNFAVIKRAN
     EQGSRWVSFK TNDNAMIANL AGRVSASAAS PLTLWANRYQ LSREEAQQLK FSQRETVLFA
     PSFSRGQGIR ASR