ID   MINC_HELPJ              Reviewed;         194 AA.
AC   Q9ZM51;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 112.
DE   RecName: Full=Probable septum site-determining protein MinC;
GN   Name=minC; OrderedLocusNames=jhp_0372;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC       ring septums. Rapidly oscillates between the poles of the cell to
CC       destabilize FtsZ filaments that have formed before they mature into
CC       polar Z rings. Prevents FtsZ polymerization (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MinC family. {ECO:0000305}.
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DR   EMBL; AE001439; AAD05953.1; -; Genomic_DNA.
DR   PIR; H71939; H71939.
DR   RefSeq; WP_000921108.1; NZ_CP011330.1.
DR   AlphaFoldDB; Q9ZM51; -.
DR   SMR; Q9ZM51; -.
DR   STRING; 85963.jhp_0372; -.
DR   EnsemblBacteria; AAD05953; AAD05953; jhp_0372.
DR   KEGG; hpj:jhp_0372; -.
DR   PATRIC; fig|85963.30.peg.639; -.
DR   eggNOG; COG0850; Bacteria.
DR   OMA; HPTPNNS; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR   Gene3D; 2.160.20.70; -; 1.
DR   HAMAP; MF_00267; MinC; 1.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR013033; MinC.
DR   InterPro; IPR036145; MinC_C_sf.
DR   InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR   Pfam; PF03775; MinC_C; 1.
DR   SUPFAM; SSF63848; SSF63848; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Septation.
FT   CHAIN           1..194
FT                   /note="Probable septum site-determining protein MinC"
FT                   /id="PRO_0000189039"
SQ   SEQUENCE   194 AA;  22302 MW;  33093F48637D0FA8 CRC64;
     MLKTNQKNVH AFEIEKQEPE AVMEFLEKNH ALLQYFLIIF KYDIESEVKA VLHKHQLLFL
     ETNRALNGRY IKTTEKDANL LKQNSPNAIE PKTTIYERNI RSGEEIYSTN HLIFLGNIHN
     GAKIISEGSV SVYGVCEGAI VCFGEYLILK EVKSAQIVFQ NKILSLKEVE RLLVNKNIKI
     ITKNDDILDI KEVL