ID   MINC_HELPY              Reviewed;         195 AA.
AC   O25693;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-DEC-2000, sequence version 2.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=Probable septum site-determining protein MinC;
GN   Name=minC; OrderedLocusNames=HP_1053;
OS   Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85962;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700392 / 26695;
RX   PubMed=9252185; DOI=10.1038/41483;
RA   Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G.,
RA   Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A.,
RA   Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N.,
RA   Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A.,
RA   McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E.,
RA   Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D.,
RA   Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S.,
RA   Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
RT   "The complete genome sequence of the gastric pathogen Helicobacter
RT   pylori.";
RL   Nature 388:539-547(1997).
CC   -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC       ring septums. Rapidly oscillates between the poles of the cell to
CC       destabilize FtsZ filaments that have formed before they mature into
CC       polar Z rings. Prevents FtsZ polymerization (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MinC family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAD08105.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE000511; AAD08105.1; ALT_INIT; Genomic_DNA.
DR   PIR; E64651; E64651.
DR   RefSeq; NP_207844.1; NC_000915.1.
DR   RefSeq; WP_000921052.1; NC_000915.1.
DR   AlphaFoldDB; O25693; -.
DR   SMR; O25693; -.
DR   IntAct; O25693; 5.
DR   STRING; 85962.C694_05445; -.
DR   PaxDb; O25693; -.
DR   EnsemblBacteria; AAD08105; AAD08105; HP_1053.
DR   KEGG; hpy:HP_1053; -.
DR   PATRIC; fig|85962.47.peg.1132; -.
DR   eggNOG; COG0850; Bacteria.
DR   OMA; HPTPNNS; -.
DR   Proteomes; UP000000429; Chromosome.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR   Gene3D; 2.160.20.70; -; 1.
DR   HAMAP; MF_00267; MinC; 1.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR013033; MinC.
DR   InterPro; IPR036145; MinC_C_sf.
DR   InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR   Pfam; PF03775; MinC_C; 1.
DR   SUPFAM; SSF63848; SSF63848; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Reference proteome; Septation.
FT   CHAIN           1..195
FT                   /note="Probable septum site-determining protein MinC"
FT                   /id="PRO_0000189038"
FT   REGION          74..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   195 AA;  22372 MW;  5C2DE7235B33C77B CRC64;
     MLKTNQKNVH AFEIEKQEPE AVIGFLEKNH ALLQYFLIIF KYDIESEVKA VLRKHQLLFL
     ETNRVLNGRH IKTMPLKDET DHPKPNHSKT EPKTTIYERH IRSGEEIYST NHLIFLGNIH
     NGAKIISEGC VSVYGVCEGA IVCFGECLIL KEVKSAQIVF QNKILSLKEV EPLLVNKNIK
     IITKNDDILD IKEVL