ID   MINC_LACE2              Reviewed;         246 AA.
AC   C4Z088;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Probable septum site-determining protein MinC {ECO:0000255|HAMAP-Rule:MF_00267};
GN   Name=minC {ECO:0000255|HAMAP-Rule:MF_00267};
GN   OrderedLocusNames=EUBELI_01000;
OS   Lachnospira eligens (strain ATCC 27750 / DSM 3376 / VPI C15-48 / C15-B4)
OS   (Eubacterium eligens).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Lachnospiraceae;
OC   Lachnospira.
OX   NCBI_TaxID=515620;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 27750 / DSM 3376 / VPI C15-48 / C15-B4;
RX   PubMed=19321416; DOI=10.1073/pnas.0901529106;
RA   Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S.,
RA   Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L.,
RA   Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C.,
RA   Hettich R.L., Gordon J.I.;
RT   "Characterizing a model human gut microbiota composed of members of its two
RT   dominant bacterial phyla.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009).
CC   -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC       ring septums. Rapidly oscillates between the poles of the cell to
CC       destabilize FtsZ filaments that have formed before they mature into
CC       polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
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DR   EMBL; CP001104; ACR72001.1; -; Genomic_DNA.
DR   RefSeq; WP_012739236.1; NC_012778.1.
DR   AlphaFoldDB; C4Z088; -.
DR   SMR; C4Z088; -.
DR   STRING; 515620.EUBELI_01000; -.
DR   EnsemblBacteria; ACR72001; ACR72001; EUBELI_01000.
DR   GeneID; 41355728; -.
DR   KEGG; eel:EUBELI_01000; -.
DR   eggNOG; COG0850; Bacteria.
DR   HOGENOM; CLU_048711_2_2_9; -.
DR   OMA; EMECAYI; -.
DR   OrthoDB; 1665744at2; -.
DR   Proteomes; UP000001476; Chromosome.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR   Gene3D; 2.160.20.70; -; 1.
DR   HAMAP; MF_00267; MinC; 1.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR013033; MinC.
DR   InterPro; IPR036145; MinC_C_sf.
DR   InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR   PANTHER; PTHR34108; PTHR34108; 1.
DR   Pfam; PF03775; MinC_C; 1.
DR   SUPFAM; SSF63848; SSF63848; 1.
DR   TIGRFAMs; TIGR01222; minC; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Reference proteome; Septation.
FT   CHAIN           1..246
FT                   /note="Probable septum site-determining protein MinC"
FT                   /id="PRO_1000204694"
SQ   SEQUENCE   246 AA;  26968 MW;  EA9ABC43A734184E CRC64;
     MNVLDNSVII KGSKNGITVF LDEEMPFEEL LENVSDKFKN ASKFFNNATM AISFDGRNLS
     AEEEKRILNV ISDVSELNIV CVLDENNDIK SVYEEAVKKA MNSFNISHQP ERQKITDPKT
     TCMFYKGTLR SGQVFEADGS VVVLGDVNPG GKVVAKGSVI VLGSLKGNIF AGVDGNENAF
     VVALEMSPMQ IKIGDIIARS SDSGVNKISK GKNKSKILEP KIAYVYDQNI YVEDLEQNAL
     DDISLD