MINC_NEIGO
ID MINC_NEIGO Reviewed; 237 AA.
AC Q9AG20;
DT 16-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Probable septum site-determining protein MinC {ECO:0000255|HAMAP-Rule:MF_00267};
GN Name=minC {ECO:0000255|HAMAP-Rule:MF_00267};
OS Neisseria gonorrhoeae.
OC Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=485;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=CH811;
RX PubMed=11160816; DOI=10.1099/00221287-147-1-225;
RA Ramirez-Arcos S., Szeto J., Beveridge T., Victor C., Francis F., Dillon J.;
RT "Deletion of the cell-division inhibitor MinC results in lysis of Neisseria
RT gonorrhoeae.";
RL Microbiology 147:225-237(2001).
CC -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC ring septums. Rapidly oscillates between the poles of the cell to
CC destabilize FtsZ filaments that have formed before they mature into
CC polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AF345908; AAK30125.1; -; Genomic_DNA.
DR RefSeq; WP_003690056.1; NZ_VAHL01000002.1.
DR AlphaFoldDB; Q9AG20; -.
DR SMR; Q9AG20; -.
DR GeneID; 66754323; -.
DR GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0051302; P:regulation of cell division; IEA:InterPro.
DR GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR Gene3D; 2.160.20.70; -; 1.
DR HAMAP; MF_00267; MinC; 1.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR013033; MinC.
DR InterPro; IPR036145; MinC_C_sf.
DR InterPro; IPR007874; MinC_N.
DR InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR PANTHER; PTHR34108; PTHR34108; 1.
DR Pfam; PF03775; MinC_C; 1.
DR Pfam; PF05209; MinC_N; 1.
DR SUPFAM; SSF63848; SSF63848; 1.
DR TIGRFAMs; TIGR01222; minC; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Septation.
FT CHAIN 1..237
FT /note="Probable septum site-determining protein MinC"
FT /id="PRO_0000189044"
SQ SEQUENCE 237 AA; 26295 MW; 83F6AC30F0B4A7A7 CRC64;
MMVYIMNAFD IKSTKMDVLS ISLHTSDLFD LEDVLVKLGK KFQESGVVPF VLDVQEFDYP
ESLDLAALVS LFSRHGMQIL GLKHSNERWA AVAMKYHLLF CLSHSENVKE LGQVEVQKTE
DGQKARKTVL ITSPVRTGQQ VYAEDGDLIV TGAVNQGAEL IADGNMHIYA PMRGRALAGA
KGDTSARIFI HSMQAELVSV AGIYRNFEQD LPDHLHKQPV QILLQDNRLV ISAIGSE