ID   MINC_NEIMB              Reviewed;         237 AA.
AC   Q9K1I0;
DT   01-DEC-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   25-MAY-2022, entry version 115.
DE   RecName: Full=Probable septum site-determining protein MinC;
GN   Name=minC; OrderedLocusNames=NMB0170;
OS   Neisseria meningitidis serogroup B (strain MC58).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC   Neisseria.
OX   NCBI_TaxID=122586;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MC58;
RX   PubMed=10710307; DOI=10.1126/science.287.5459.1809;
RA   Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E.,
RA   Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C.,
RA   Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H.,
RA   Salzberg S.L., White O., Fleischmann R.D., Dougherty B.A., Mason T.M.,
RA   Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D.,
RA   Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V.,
RA   Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M.,
RA   Moxon E.R., Rappuoli R., Venter J.C.;
RT   "Complete genome sequence of Neisseria meningitidis serogroup B strain
RT   MC58.";
RL   Science 287:1809-1815(2000).
CC   -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC       ring septums. Rapidly oscillates between the poles of the cell to
CC       destabilize FtsZ filaments that have formed before they mature into
CC       polar Z rings. Prevents FtsZ polymerization (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MinC family. {ECO:0000305}.
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DR   EMBL; AE002098; AAF40627.1; -; Genomic_DNA.
DR   PIR; B81230; B81230.
DR   RefSeq; NP_273228.1; NC_003112.2.
DR   RefSeq; WP_002224775.1; NC_003112.2.
DR   AlphaFoldDB; Q9K1I0; -.
DR   SMR; Q9K1I0; -.
DR   STRING; 122586.NMB0170; -.
DR   PaxDb; Q9K1I0; -.
DR   EnsemblBacteria; AAF40627; AAF40627; NMB0170.
DR   KEGG; nme:NMB0170; -.
DR   PATRIC; fig|122586.8.peg.211; -.
DR   HOGENOM; CLU_067812_0_0_4; -.
DR   OMA; AVAMKYH; -.
DR   Proteomes; UP000000425; Chromosome.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:0051302; P:regulation of cell division; IEA:InterPro.
DR   GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR   Gene3D; 2.160.20.70; -; 1.
DR   HAMAP; MF_00267; MinC; 1.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR013033; MinC.
DR   InterPro; IPR036145; MinC_C_sf.
DR   InterPro; IPR007874; MinC_N.
DR   InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR   PANTHER; PTHR34108; PTHR34108; 1.
DR   Pfam; PF03775; MinC_C; 1.
DR   Pfam; PF05209; MinC_N; 1.
DR   SUPFAM; SSF63848; SSF63848; 1.
DR   TIGRFAMs; TIGR01222; minC; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Reference proteome; Septation.
FT   CHAIN           1..237
FT                   /note="Probable septum site-determining protein MinC"
FT                   /id="PRO_0000189046"
SQ   SEQUENCE   237 AA;  26221 MW;  E42BD0C1B9C16853 CRC64;
     MMVYIMNAFD IKSTKMDVLS ISLHTSDLFD LEDVLVKLGK KFQESGVVPF VLDVQEFDYP
     ESLDLAALVS LFSRHGMQIL GLKHSNERWA AAAMKYHLLF CLSHSENVKE LGQVEVQKTE
     DGQKARKTVL ITSPVRTGQQ VYAEDGDLIV TGAVSQGAEL IADGNIHIYA PMRGRALAGA
     KGDTSARIFI HSMQAELVSV AGIYRNFEQD LPNHLHKQPV QILLQDNRLV ISAIGSE