MINC_NEIMF
ID MINC_NEIMF Reviewed; 237 AA.
AC A1KRK1;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 06-FEB-2007, sequence version 1.
DT 25-MAY-2022, entry version 86.
DE RecName: Full=Probable septum site-determining protein MinC {ECO:0000255|HAMAP-Rule:MF_00267};
GN Name=minC {ECO:0000255|HAMAP-Rule:MF_00267}; OrderedLocusNames=NMC0160;
OS Neisseria meningitidis serogroup C / serotype 2a (strain ATCC 700532 / DSM
OS 15464 / FAM18).
OC Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=272831;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700532 / DSM 15464 / FAM18;
RX PubMed=17305430; DOI=10.1371/journal.pgen.0030023;
RA Bentley S.D., Vernikos G.S., Snyder L.A.S., Churcher C., Arrowsmith C.,
RA Chillingworth T., Cronin A., Davis P.H., Holroyd N.E., Jagels K.,
RA Maddison M., Moule S., Rabbinowitsch E., Sharp S., Unwin L., Whitehead S.,
RA Quail M.A., Achtman M., Barrell B.G., Saunders N.J., Parkhill J.;
RT "Meningococcal genetic variation mechanisms viewed through comparative
RT analysis of serogroup C strain FAM18.";
RL PLoS Genet. 3:230-240(2007).
CC -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC ring septums. Rapidly oscillates between the poles of the cell to
CC destabilize FtsZ filaments that have formed before they mature into
CC polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
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DR EMBL; AM421808; CAM09479.1; -; Genomic_DNA.
DR RefSeq; WP_002220172.1; NC_008767.1.
DR AlphaFoldDB; A1KRK1; -.
DR SMR; A1KRK1; -.
DR EnsemblBacteria; CAM09479; CAM09479; NMC0160.
DR KEGG; nmc:NMC0160; -.
DR HOGENOM; CLU_067812_0_0_4; -.
DR OMA; AVAMKYH; -.
DR OrthoDB; 1665744at2; -.
DR Proteomes; UP000002286; Chromosome.
DR GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0051302; P:regulation of cell division; IEA:InterPro.
DR GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR Gene3D; 2.160.20.70; -; 1.
DR HAMAP; MF_00267; MinC; 1.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR013033; MinC.
DR InterPro; IPR036145; MinC_C_sf.
DR InterPro; IPR007874; MinC_N.
DR InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR PANTHER; PTHR34108; PTHR34108; 1.
DR Pfam; PF03775; MinC_C; 1.
DR Pfam; PF05209; MinC_N; 1.
DR SUPFAM; SSF63848; SSF63848; 1.
DR TIGRFAMs; TIGR01222; minC; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Septation.
FT CHAIN 1..237
FT /note="Probable septum site-determining protein MinC"
FT /id="PRO_1000047837"
SQ SEQUENCE 237 AA; 26207 MW; 442ED0C1B9C46850 CRC64;
MMVYIMNAFD IKSTKMDVLS ISLHTSDLFD LEDVLVKLGK KFQESGVVPF VLDVQEFDYP
ESLDLAALVS LFSRHGMQIL GLKHSNERWA AAAMKYHLLF CLSHSENVKE LGQVEVQNTE
DGQKARKTVL ITSPVRTGQQ VYAEDGDLIV TGAVSQGAEL IADGNIHIYA PMRGRALAGA
KGDTSARIFI HSMQAELVSV AGIYRNFEQD LPNHLHKQPV QILLQDNRLV ISAIGSE