MINC_PSEAB
ID MINC_PSEAB Reviewed; 263 AA.
AC Q02Q74;
DT 15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT 14-NOV-2006, sequence version 1.
DT 03-AUG-2022, entry version 89.
DE RecName: Full=Probable septum site-determining protein MinC {ECO:0000255|HAMAP-Rule:MF_00267};
GN Name=minC {ECO:0000255|HAMAP-Rule:MF_00267}; OrderedLocusNames=PA14_22040;
OS Pseudomonas aeruginosa (strain UCBPP-PA14).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC Pseudomonadaceae; Pseudomonas.
OX NCBI_TaxID=208963;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=UCBPP-PA14;
RX PubMed=17038190; DOI=10.1186/gb-2006-7-10-r90;
RA Lee D.G., Urbach J.M., Wu G., Liberati N.T., Feinbaum R.L., Miyata S.,
RA Diggins L.T., He J., Saucier M., Deziel E., Friedman L., Li L., Grills G.,
RA Montgomery K., Kucherlapati R., Rahme L.G., Ausubel F.M.;
RT "Genomic analysis reveals that Pseudomonas aeruginosa virulence is
RT combinatorial.";
RL Genome Biol. 7:R90.1-R90.14(2006).
CC -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC ring septums. Rapidly oscillates between the poles of the cell to
CC destabilize FtsZ filaments that have formed before they mature into
CC polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
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DR EMBL; CP000438; ABJ12492.1; -; Genomic_DNA.
DR RefSeq; WP_003109174.1; NZ_CP034244.1.
DR AlphaFoldDB; Q02Q74; -.
DR SMR; Q02Q74; -.
DR PRIDE; Q02Q74; -.
DR EnsemblBacteria; ABJ12492; ABJ12492; PA14_22040.
DR KEGG; pau:PA14_22040; -.
DR HOGENOM; CLU_067812_0_1_6; -.
DR OMA; RRDPLWG; -.
DR BioCyc; PAER208963:G1G74-1831-MON; -.
DR Proteomes; UP000000653; Chromosome.
DR GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0051302; P:regulation of cell division; IEA:InterPro.
DR GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR Gene3D; 2.160.20.70; -; 1.
DR HAMAP; MF_00267; MinC; 1.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR013033; MinC.
DR InterPro; IPR036145; MinC_C_sf.
DR InterPro; IPR007874; MinC_N.
DR InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR PANTHER; PTHR34108; PTHR34108; 1.
DR Pfam; PF03775; MinC_C; 1.
DR Pfam; PF05209; MinC_N; 1.
DR SUPFAM; SSF63848; SSF63848; 1.
DR TIGRFAMs; TIGR01222; minC; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Septation.
FT CHAIN 1..263
FT /note="Probable septum site-determining protein MinC"
FT /id="PRO_1000047842"
FT REGION 107..159
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 140..154
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 263 AA; 28110 MW; CEDE75A5B71B5657 CRC64;
MSQADLLDQD PVFQLKGSML AVTILELAHN DLARLERQLA DKVAQAPNFF RDTPLVMALD
KLPEGEGRLD LPALLEVCRR HGLRTLAIRA GREEDIAAAQ ALDLPVLPPS GARERPLDIK
DSAPRKPAEE PSPSAGEARP EPAKAEEKPA DPVSRPTKVV KTPVRGGMQI YAAGGDLIVL
AAVSPGAELL ADGNIHVYGP MRGRALAGVK GDATARIFCQ QLAAELVSIA GNYKVAEDLR
RSPQWGKAVH VSLSGDVLNI TRL