ID   MINC_SALTY              Reviewed;         235 AA.
AC   P65359; Q8XEJ9;
DT   11-OCT-2004, integrated into UniProtKB/Swiss-Prot.
DT   11-OCT-2004, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Septum site-determining protein MinC;
GN   Name=minC {ECO:0000255|HAMAP-Rule:MF_00267}; OrderedLocusNames=STM1814;
OS   Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=99287;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=LT2 / SGSC1412 / ATCC 700720;
RX   PubMed=11677609; DOI=10.1038/35101614;
RA   McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P.,
RA   Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D.,
RA   Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E.,
RA   Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R.,
RA   Wilson R.K.;
RT   "Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
RL   Nature 413:852-856(2001).
CC   -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC       ring septums. Rapidly oscillates between the poles of the cell to
CC       destabilize FtsZ filaments that have formed before they mature into
CC       polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE006468; AAL20729.1; -; Genomic_DNA.
DR   RefSeq; NP_460770.1; NC_003197.2.
DR   RefSeq; WP_000072527.1; NC_003197.2.
DR   PDB; 3GHF; X-ray; 2.20 A; A=2-110.
DR   PDBsum; 3GHF; -.
DR   AlphaFoldDB; P65359; -.
DR   SMR; P65359; -.
DR   STRING; 99287.STM1814; -.
DR   PaxDb; P65359; -.
DR   EnsemblBacteria; AAL20729; AAL20729; STM1814.
DR   GeneID; 1253333; -.
DR   KEGG; stm:STM1814; -.
DR   PATRIC; fig|99287.12.peg.1914; -.
DR   HOGENOM; CLU_067812_0_1_6; -.
DR   OMA; RRDPLWG; -.
DR   PhylomeDB; P65359; -.
DR   BioCyc; SENT99287:STM1814-MON; -.
DR   EvolutionaryTrace; P65359; -.
DR   Proteomes; UP000001014; Chromosome.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:0051302; P:regulation of cell division; IEA:InterPro.
DR   GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR   Gene3D; 2.160.20.70; -; 1.
DR   HAMAP; MF_00267; MinC; 1.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR013033; MinC.
DR   InterPro; IPR036145; MinC_C_sf.
DR   InterPro; IPR007874; MinC_N.
DR   InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR   PANTHER; PTHR34108; PTHR34108; 1.
DR   Pfam; PF03775; MinC_C; 1.
DR   Pfam; PF05209; MinC_N; 1.
DR   SUPFAM; SSF63848; SSF63848; 1.
DR   TIGRFAMs; TIGR01222; minC; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Cell cycle; Cell division; Reference proteome; Septation.
FT   CHAIN           1..235
FT                   /note="Septum site-determining protein MinC"
FT                   /id="PRO_0000189060"
FT   REGION          104..125
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   STRAND          16..22
FT                   /evidence="ECO:0007829|PDB:3GHF"
FT   HELIX           25..38
FT                   /evidence="ECO:0007829|PDB:3GHF"
FT   HELIX           40..43
FT                   /evidence="ECO:0007829|PDB:3GHF"
FT   STRAND          47..54
FT                   /evidence="ECO:0007829|PDB:3GHF"
FT   HELIX           61..69
FT                   /evidence="ECO:0007829|PDB:3GHF"
FT   TURN            70..72
FT                   /evidence="ECO:0007829|PDB:3GHF"
FT   STRAND          74..80
FT                   /evidence="ECO:0007829|PDB:3GHF"
FT   HELIX           84..92
FT                   /evidence="ECO:0007829|PDB:3GHF"
SQ   SEQUENCE   235 AA;  25246 MW;  FF4165927F34056A CRC64;
     MSNTPIELKG SSFTLSVVHL HEAEPEVIRQ ALEDKIAQAP AFLKHAPVVI NVSGLESPVN
     WPELHKIVTS TGLRIIGVSG CKDASLKVEI DRMGLPLLTE GKEKAVRPAP VEPATPSEPP
     QNANPITKTR LIDVPVRSGQ RIYAPQCDLI VTSHVSAGAE LIADGNIHVY GMMRGRALAG
     ASGDREAQIF CTHLTAELVS IAGVYWLSDK IPAEFYGKAA RLRLADNALT VQPLN