ID   MINC_THESQ              Reviewed;         210 AA.
AC   B1L862;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   29-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 80.
DE   RecName: Full=Probable septum site-determining protein MinC {ECO:0000255|HAMAP-Rule:MF_00267};
GN   Name=minC {ECO:0000255|HAMAP-Rule:MF_00267}; OrderedLocusNames=TRQ2_1761;
OS   Thermotoga sp. (strain RQ2).
OC   Bacteria; Thermotogae; Thermotogales; Thermotogaceae; Thermotoga;
OC   unclassified Thermotoga.
OX   NCBI_TaxID=126740;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=RQ2;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E.,
RA   Tice H., Bruce D.B., Goodwin L., Pitluck S., Saunders E., Brettin T.,
RA   Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L.,
RA   Kyrpides N., Mikhailova N., Nelson K., Gogarten J.P., Noll K.,
RA   Richardson P.;
RT   "Complete sequence of Thermotoga sp. RQ2.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC       ring septums. Rapidly oscillates between the poles of the cell to
CC       destabilize FtsZ filaments that have formed before they mature into
CC       polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
CC   -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC       Rule:MF_00267}.
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DR   EMBL; CP000969; ACB10092.1; -; Genomic_DNA.
DR   RefSeq; WP_012311327.1; NC_010483.1.
DR   AlphaFoldDB; B1L862; -.
DR   SMR; B1L862; -.
DR   EnsemblBacteria; ACB10092; ACB10092; TRQ2_1761.
DR   KEGG; trq:TRQ2_1761; -.
DR   HOGENOM; CLU_048711_2_1_0; -.
DR   OMA; EMECAYI; -.
DR   OrthoDB; 1665744at2; -.
DR   Proteomes; UP000001687; Chromosome.
DR   GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR   GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR   GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR   Gene3D; 2.160.20.70; -; 1.
DR   HAMAP; MF_00267; MinC; 1.
DR   InterPro; IPR016098; CAP/MinC_C.
DR   InterPro; IPR013033; MinC.
DR   InterPro; IPR036145; MinC_C_sf.
DR   InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR   PANTHER; PTHR34108; PTHR34108; 1.
DR   Pfam; PF03775; MinC_C; 1.
DR   SUPFAM; SSF63848; SSF63848; 1.
DR   TIGRFAMs; TIGR01222; minC; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Septation.
FT   CHAIN           1..210
FT                   /note="Probable septum site-determining protein MinC"
FT                   /id="PRO_1000114298"
SQ   SEQUENCE   210 AA;  22813 MW;  2B624D350B9E45E4 CRC64;
     MVDFKMTKEG LILLIKDYQN LEEVLNAISA RITQMGGFFA KGDRISLMIE NHNKHSQDIP
     KIVSHLRNLG LEVSQILVGS TVEGKENDLR VQSRTTVEST GKVIKRNIRS GQTVVHSGDV
     IVFGNVNKGA EILAGGSVVV FGKAQGNIRA GLNEGEQAVV AALDLQTSLI QIAGFITHSK
     GEENVPSIAH VKGNRIVIEP FDKVSFERSE