MINC_VIBCM
ID MINC_VIBCM Reviewed; 220 AA.
AC C3LNR2;
DT 28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT 16-JUN-2009, sequence version 1.
DT 25-MAY-2022, entry version 73.
DE RecName: Full=Probable septum site-determining protein MinC {ECO:0000255|HAMAP-Rule:MF_00267};
GN Name=minC {ECO:0000255|HAMAP-Rule:MF_00267}; OrderedLocusNames=VCM66_1883;
OS Vibrio cholerae serotype O1 (strain M66-2).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Vibrionales; Vibrionaceae;
OC Vibrio.
OX NCBI_TaxID=579112;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=M66-2;
RX PubMed=19115014; DOI=10.1371/journal.pone.0004053;
RA Feng L., Reeves P.R., Lan R., Ren Y., Gao C., Zhou Z., Ren Y., Cheng J.,
RA Wang W., Wang J., Qian W., Li D., Wang L.;
RT "A recalibrated molecular clock and independent origins for the cholera
RT pandemic clones.";
RL PLoS ONE 3:E4053-E4053(2008).
CC -!- FUNCTION: Cell division inhibitor that blocks the formation of polar Z
CC ring septums. Rapidly oscillates between the poles of the cell to
CC destabilize FtsZ filaments that have formed before they mature into
CC polar Z rings. Prevents FtsZ polymerization. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SUBUNIT: Interacts with MinD and FtsZ. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
CC -!- SIMILARITY: Belongs to the MinC family. {ECO:0000255|HAMAP-
CC Rule:MF_00267}.
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DR EMBL; CP001233; ACP06188.1; -; Genomic_DNA.
DR RefSeq; WP_000042146.1; NC_012578.1.
DR AlphaFoldDB; C3LNR2; -.
DR SMR; C3LNR2; -.
DR EnsemblBacteria; ACP06188; ACP06188; VCM66_1883.
DR GeneID; 57740585; -.
DR KEGG; vcm:VCM66_1883; -.
DR HOGENOM; CLU_067812_0_1_6; -.
DR OMA; RRDPLWG; -.
DR Proteomes; UP000001217; Chromosome I.
DR GO; GO:0000902; P:cell morphogenesis; IEA:InterPro.
DR GO; GO:0000917; P:division septum assembly; IEA:UniProtKB-KW.
DR GO; GO:0051302; P:regulation of cell division; IEA:InterPro.
DR GO; GO:1901891; P:regulation of cell septum assembly; IEA:InterPro.
DR Gene3D; 2.160.20.70; -; 1.
DR HAMAP; MF_00267; MinC; 1.
DR InterPro; IPR016098; CAP/MinC_C.
DR InterPro; IPR013033; MinC.
DR InterPro; IPR036145; MinC_C_sf.
DR InterPro; IPR007874; MinC_N.
DR InterPro; IPR005526; Septum_form_inhib_MinC_C.
DR PANTHER; PTHR34108; PTHR34108; 1.
DR Pfam; PF03775; MinC_C; 1.
DR Pfam; PF05209; MinC_N; 1.
DR SUPFAM; SSF63848; SSF63848; 1.
DR TIGRFAMs; TIGR01222; minC; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Septation.
FT CHAIN 1..220
FT /note="Probable septum site-determining protein MinC"
FT /id="PRO_1000191261"
SQ SEQUENCE 220 AA; 23646 MW; CA8E56BBFAC60370 CRC64;
MSKNPDLKGS SFTLSVLHLS DNQIAHTVQF LQEKIAQAPA FFANAPVVIN VAKVEGDIDY
PALKQGISQA GLIPVGVTGC KDKRSQNLAV EAGFAVMTAT NSPAQAPAQM APTKVIRTPV
RSGQQIYAKD GDLVILSHVS AGAEVIADGS IHIYGTLRGR AIAGASGQRE ARIICHDLQA
ELISIAGRYW LSDQIESQFW QQRVMLSMTD ESLYLETLTI