ID   MINE_CLOBH              Reviewed;          87 AA.
AC   A5I676; A7G7F9;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   26-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Cell division topological specificity factor {ECO:0000255|HAMAP-Rule:MF_00262};
GN   Name=minE {ECO:0000255|HAMAP-Rule:MF_00262};
GN   OrderedLocusNames=CBO2996, CLC_2893;
OS   Clostridium botulinum (strain Hall / ATCC 3502 / NCTC 13319 / Type A).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=441771;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hall / ATCC 3502 / NCTC 13319 / Type A;
RX   PubMed=17519437; DOI=10.1101/gr.6282807;
RA   Sebaihia M., Peck M.W., Minton N.P., Thomson N.R., Holden M.T.G.,
RA   Mitchell W.J., Carter A.T., Bentley S.D., Mason D.R., Crossman L.,
RA   Paul C.J., Ivens A., Wells-Bennik M.H.J., Davis I.J., Cerdeno-Tarraga A.M.,
RA   Churcher C., Quail M.A., Chillingworth T., Feltwell T., Fraser A.,
RA   Goodhead I., Hance Z., Jagels K., Larke N., Maddison M., Moule S.,
RA   Mungall K., Norbertczak H., Rabbinowitsch E., Sanders M., Simmonds M.,
RA   White B., Whithead S., Parkhill J.;
RT   "Genome sequence of a proteolytic (Group I) Clostridium botulinum strain
RT   Hall A and comparative analysis of the clostridial genomes.";
RL   Genome Res. 17:1082-1092(2007).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Hall / ATCC 3502 / NCTC 13319 / Type A;
RX   PubMed=18060065; DOI=10.1371/journal.pone.0001271;
RA   Smith T.J., Hill K.K., Foley B.T., Detter J.C., Munk A.C., Bruce D.C.,
RA   Doggett N.A., Smith L.A., Marks J.D., Xie G., Brettin T.S.;
RT   "Analysis of the neurotoxin complex genes in Clostridium botulinum A1-A4
RT   and B1 strains: BoNT/A3, /Ba4 and /B1 clusters are located within
RT   plasmids.";
RL   PLoS ONE 2:E1271-E1271(2007).
CC   -!- FUNCTION: Prevents the cell division inhibition by proteins MinC and
CC       MinD at internal division sites while permitting inhibition at polar
CC       sites. This ensures cell division at the proper site by restricting the
CC       formation of a division septum at the midpoint of the long axis of the
CC       cell. {ECO:0000255|HAMAP-Rule:MF_00262}.
CC   -!- SIMILARITY: Belongs to the MinE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00262}.
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DR   EMBL; CP000727; ABS37438.1; -; Genomic_DNA.
DR   EMBL; AM412317; CAL84558.1; -; Genomic_DNA.
DR   RefSeq; WP_003358099.1; NC_009698.1.
DR   RefSeq; YP_001255488.1; NC_009495.1.
DR   RefSeq; YP_001388724.1; NC_009698.1.
DR   AlphaFoldDB; A5I676; -.
DR   GeneID; 5187008; -.
DR   KEGG; cbh:CLC_2893; -.
DR   KEGG; cbo:CBO2996; -.
DR   PATRIC; fig|413999.7.peg.2974; -.
DR   HOGENOM; CLU_137929_1_0_9; -.
DR   OMA; VHDRANV; -.
DR   PRO; PR:A5I676; -.
DR   Proteomes; UP000001986; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0000918; P:division septum site selection; IBA:GO_Central.
DR   GO; GO:0032955; P:regulation of division septum assembly; IBA:GO_Central.
DR   Gene3D; 3.30.1070.10; -; 1.
DR   HAMAP; MF_00262; MinE; 1.
DR   InterPro; IPR005527; MinE.
DR   InterPro; IPR036707; MinE_sf.
DR   PANTHER; PTHR33404; PTHR33404; 1.
DR   Pfam; PF03776; MinE; 1.
DR   SUPFAM; SSF55229; SSF55229; 1.
DR   TIGRFAMs; TIGR01215; minE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Reference proteome.
FT   CHAIN           1..87
FT                   /note="Cell division topological specificity factor"
FT                   /id="PRO_1000047781"
SQ   SEQUENCE   87 AA;  10027 MW;  54AFB015D9E578A8 CRC64;
     MDLFKFFSKQ SSKDVAKERL KLILIQDRNS ISPDVLESIR EDMLKVISKY IEIDNEDVDI
     KMSSVEEIEG MSPALIASIP IKRIKKK