ID   MINE_CLOP1              Reviewed;          90 AA.
AC   Q0TNH5;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Cell division topological specificity factor {ECO:0000255|HAMAP-Rule:MF_00262};
GN   Name=minE {ECO:0000255|HAMAP-Rule:MF_00262}; OrderedLocusNames=CPF_2392;
OS   Clostridium perfringens (strain ATCC 13124 / DSM 756 / JCM 1290 / NCIMB
OS   6125 / NCTC 8237 / Type A).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=195103;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 13124 / DSM 756 / JCM 1290 / NCIMB 6125 / NCTC 8237 / S 107 /
RC   Type A;
RX   PubMed=16825665; DOI=10.1101/gr.5238106;
RA   Myers G.S.A., Rasko D.A., Cheung J.K., Ravel J., Seshadri R., DeBoy R.T.,
RA   Ren Q., Varga J., Awad M.M., Brinkac L.M., Daugherty S.C., Haft D.H.,
RA   Dodson R.J., Madupu R., Nelson W.C., Rosovitz M.J., Sullivan S.A.,
RA   Khouri H., Dimitrov G.I., Watkins K.L., Mulligan S., Benton J., Radune D.,
RA   Fisher D.J., Atkins H.S., Hiscox T., Jost B.H., Billington S.J.,
RA   Songer J.G., McClane B.A., Titball R.W., Rood J.I., Melville S.B.,
RA   Paulsen I.T.;
RT   "Skewed genomic variability in strains of the toxigenic bacterial pathogen,
RT   Clostridium perfringens.";
RL   Genome Res. 16:1031-1040(2006).
CC   -!- FUNCTION: Prevents the cell division inhibition by proteins MinC and
CC       MinD at internal division sites while permitting inhibition at polar
CC       sites. This ensures cell division at the proper site by restricting the
CC       formation of a division septum at the midpoint of the long axis of the
CC       cell. {ECO:0000255|HAMAP-Rule:MF_00262}.
CC   -!- SIMILARITY: Belongs to the MinE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00262}.
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DR   EMBL; CP000246; ABG82739.1; -; Genomic_DNA.
DR   RefSeq; WP_003452508.1; NC_008261.1.
DR   AlphaFoldDB; Q0TNH5; -.
DR   STRING; 195103.CPF_2392; -.
DR   EnsemblBacteria; ABG82739; ABG82739; CPF_2392.
DR   GeneID; 29570500; -.
DR   KEGG; cpf:CPF_2392; -.
DR   eggNOG; COG0851; Bacteria.
DR   HOGENOM; CLU_137929_1_0_9; -.
DR   OMA; VHDRANV; -.
DR   OrthoDB; 2038628at2; -.
DR   Proteomes; UP000001823; Chromosome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0032955; P:regulation of division septum assembly; IEA:InterPro.
DR   Gene3D; 3.30.1070.10; -; 1.
DR   HAMAP; MF_00262; MinE; 1.
DR   InterPro; IPR005527; MinE.
DR   InterPro; IPR036707; MinE_sf.
DR   Pfam; PF03776; MinE; 1.
DR   SUPFAM; SSF55229; SSF55229; 1.
DR   TIGRFAMs; TIGR01215; minE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division.
FT   CHAIN           1..90
FT                   /note="Cell division topological specificity factor"
FT                   /id="PRO_0000298102"
SQ   SEQUENCE   90 AA;  10128 MW;  F881B16F95880ACD CRC64;
     MSFLNVFSSR PTPKQVAKDR LKVILIHDRG ELSDEVLDKI RLEILDVLSK YVEIENEDVD
     ITVTKSNPIE GESPSLVANI PIKNIKGKAR