ID   MINE_ECO7I              Reviewed;          88 AA.
AC   B7NJG8;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-MAR-2009, sequence version 1.
DT   25-MAY-2022, entry version 64.
DE   RecName: Full=Cell division topological specificity factor {ECO:0000255|HAMAP-Rule:MF_00262};
GN   Name=minE {ECO:0000255|HAMAP-Rule:MF_00262};
GN   OrderedLocusNames=ECIAI39_1899;
OS   Escherichia coli O7:K1 (strain IAI39 / ExPEC).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=585057;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=IAI39 / ExPEC;
RX   PubMed=19165319; DOI=10.1371/journal.pgen.1000344;
RA   Touchon M., Hoede C., Tenaillon O., Barbe V., Baeriswyl S., Bidet P.,
RA   Bingen E., Bonacorsi S., Bouchier C., Bouvet O., Calteau A., Chiapello H.,
RA   Clermont O., Cruveiller S., Danchin A., Diard M., Dossat C., Karoui M.E.,
RA   Frapy E., Garry L., Ghigo J.M., Gilles A.M., Johnson J., Le Bouguenec C.,
RA   Lescat M., Mangenot S., Martinez-Jehanne V., Matic I., Nassif X., Oztas S.,
RA   Petit M.A., Pichon C., Rouy Z., Ruf C.S., Schneider D., Tourret J.,
RA   Vacherie B., Vallenet D., Medigue C., Rocha E.P.C., Denamur E.;
RT   "Organised genome dynamics in the Escherichia coli species results in
RT   highly diverse adaptive paths.";
RL   PLoS Genet. 5:E1000344-E1000344(2009).
CC   -!- FUNCTION: Prevents the cell division inhibition by proteins MinC and
CC       MinD at internal division sites while permitting inhibition at polar
CC       sites. This ensures cell division at the proper site by restricting the
CC       formation of a division septum at the midpoint of the long axis of the
CC       cell. {ECO:0000255|HAMAP-Rule:MF_00262}.
CC   -!- SIMILARITY: Belongs to the MinE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00262}.
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DR   EMBL; CU928164; CAR18030.1; -; Genomic_DNA.
DR   RefSeq; WP_001185665.1; NC_011750.1.
DR   RefSeq; YP_002407876.1; NC_011750.1.
DR   AlphaFoldDB; B7NJG8; -.
DR   SMR; B7NJG8; -.
DR   STRING; 585057.ECIAI39_1899; -.
DR   EnsemblBacteria; CAR18030; CAR18030; ECIAI39_1899.
DR   GeneID; 67415436; -.
DR   KEGG; ect:ECIAI39_1899; -.
DR   PATRIC; fig|585057.6.peg.1977; -.
DR   HOGENOM; CLU_137929_2_2_6; -.
DR   OMA; QIIVARE; -.
DR   Proteomes; UP000000749; Chromosome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0032955; P:regulation of division septum assembly; IEA:InterPro.
DR   Gene3D; 3.30.1070.10; -; 1.
DR   HAMAP; MF_00262; MinE; 1.
DR   InterPro; IPR005527; MinE.
DR   InterPro; IPR036707; MinE_sf.
DR   Pfam; PF03776; MinE; 1.
DR   SUPFAM; SSF55229; SSF55229; 1.
DR   TIGRFAMs; TIGR01215; minE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division.
FT   CHAIN           1..88
FT                   /note="Cell division topological specificity factor"
FT                   /id="PRO_1000191282"
SQ   SEQUENCE   88 AA;  10235 MW;  04DDFB4EA24F96C1 CRC64;
     MALLDFFLSR KKNTANIAKE RLQIIVAERR RSDAEPHYLP QLRKDILEVI CKYVQIDPEM
     VTVQLEQKDG DISILELNVT LPEAEELK