ID   MINE_FUSNN              Reviewed;          99 AA.
AC   Q8RGV0;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Cell division topological specificity factor {ECO:0000255|HAMAP-Rule:MF_00262};
GN   Name=minE {ECO:0000255|HAMAP-Rule:MF_00262}; OrderedLocusNames=FN0177;
OS   Fusobacterium nucleatum subsp. nucleatum (strain ATCC 25586 / DSM 15643 /
OS   BCRC 10681 / CIP 101130 / JCM 8532 / KCTC 2640 / LMG 13131 / VPI 4355).
OC   Bacteria; Fusobacteria; Fusobacteriales; Fusobacteriaceae; Fusobacterium.
OX   NCBI_TaxID=190304;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25586 / DSM 15643 / BCRC 10681 / CIP 101130 / JCM 8532 / KCTC
RC   2640 / LMG 13131 / VPI 4355;
RX   PubMed=11889109; DOI=10.1128/jb.184.7.2005-2018.2002;
RA   Kapatral V., Anderson I., Ivanova N., Reznik G., Los T., Lykidis A.,
RA   Bhattacharyya A., Bartman A., Gardner W., Grechkin G., Zhu L., Vasieva O.,
RA   Chu L., Kogan Y., Chaga O., Goltsman E., Bernal A., Larsen N., D'Souza M.,
RA   Walunas T., Pusch G., Haselkorn R., Fonstein M., Kyrpides N.C.,
RA   Overbeek R.;
RT   "Genome sequence and analysis of the oral bacterium Fusobacterium nucleatum
RT   strain ATCC 25586.";
RL   J. Bacteriol. 184:2005-2018(2002).
CC   -!- FUNCTION: Prevents the cell division inhibition by proteins MinC and
CC       MinD at internal division sites while permitting inhibition at polar
CC       sites. This ensures cell division at the proper site by restricting the
CC       formation of a division septum at the midpoint of the long axis of the
CC       cell. {ECO:0000255|HAMAP-Rule:MF_00262}.
CC   -!- SIMILARITY: Belongs to the MinE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00262}.
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DR   EMBL; AE009951; AAL94383.1; -; Genomic_DNA.
DR   RefSeq; NP_603084.1; NC_003454.1.
DR   AlphaFoldDB; Q8RGV0; -.
DR   STRING; 190304.FN0177; -.
DR   EnsemblBacteria; AAL94383; AAL94383; FN0177.
DR   KEGG; fnu:FN0177; -.
DR   PATRIC; fig|190304.8.peg.758; -.
DR   eggNOG; COG0851; Bacteria.
DR   HOGENOM; CLU_137929_1_0_0; -.
DR   InParanoid; Q8RGV0; -.
DR   OMA; VHDRANV; -.
DR   BioCyc; FNUC190304:G1FZS-779-MON; -.
DR   Proteomes; UP000002521; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR   GO; GO:0000918; P:division septum site selection; IBA:GO_Central.
DR   GO; GO:0032955; P:regulation of division septum assembly; IBA:GO_Central.
DR   Gene3D; 3.30.1070.10; -; 1.
DR   HAMAP; MF_00262; MinE; 1.
DR   InterPro; IPR005527; MinE.
DR   InterPro; IPR036707; MinE_sf.
DR   Pfam; PF03776; MinE; 1.
DR   SUPFAM; SSF55229; SSF55229; 1.
DR   TIGRFAMs; TIGR01215; minE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Reference proteome.
FT   CHAIN           1..99
FT                   /note="Cell division topological specificity factor"
FT                   /id="PRO_0000298120"
SQ   SEQUENCE   99 AA;  11491 MW;  3AF75EC4B6E7DD0E CRC64;
     MGFFSNFFKK ENSKDDAKNR LKLVLIQDRA MLPSGVLENM KDDILKVLSK YVEIEKSKLN
     IEMCPYEDDP RKIALVANIP ILKSSTREVT KTTKQQKRK