ID   MINE_HAMD5              Reviewed;          94 AA.
AC   C4K838;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Cell division topological specificity factor {ECO:0000255|HAMAP-Rule:MF_00262};
GN   Name=minE {ECO:0000255|HAMAP-Rule:MF_00262}; OrderedLocusNames=HDEF_0022;
OS   Hamiltonella defensa subsp. Acyrthosiphon pisum (strain 5AT).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; aphid secondary symbionts; Candidatus Hamiltonella.
OX   NCBI_TaxID=572265;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=5AT;
RX   PubMed=19451630; DOI=10.1073/pnas.0900194106;
RA   Degnan P.H., Yu Y., Sisneros N., Wing R.A., Moran N.A.;
RT   "Hamiltonella defensa, genome evolution of protective bacterial
RT   endosymbiont from pathogenic ancestors.";
RL   Proc. Natl. Acad. Sci. U.S.A. 106:9063-9068(2009).
CC   -!- FUNCTION: Prevents the cell division inhibition by proteins MinC and
CC       MinD at internal division sites while permitting inhibition at polar
CC       sites. This ensures cell division at the proper site by restricting the
CC       formation of a division septum at the midpoint of the long axis of the
CC       cell. {ECO:0000255|HAMAP-Rule:MF_00262}.
CC   -!- SIMILARITY: Belongs to the MinE family. {ECO:0000255|HAMAP-
CC       Rule:MF_00262}.
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DR   EMBL; CP001277; ACQ66798.1; -; Genomic_DNA.
DR   RefSeq; WP_012737763.1; NC_012751.1.
DR   AlphaFoldDB; C4K838; -.
DR   SMR; C4K838; -.
DR   STRING; 572265.HDEF_0022; -.
DR   EnsemblBacteria; ACQ66798; ACQ66798; HDEF_0022.
DR   GeneID; 66259966; -.
DR   KEGG; hde:HDEF_0022; -.
DR   eggNOG; COG0851; Bacteria.
DR   HOGENOM; CLU_137929_2_2_6; -.
DR   OMA; QIIVARE; -.
DR   Proteomes; UP000002334; Chromosome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0032955; P:regulation of division septum assembly; IEA:InterPro.
DR   Gene3D; 3.30.1070.10; -; 1.
DR   HAMAP; MF_00262; MinE; 1.
DR   InterPro; IPR005527; MinE.
DR   InterPro; IPR036707; MinE_sf.
DR   Pfam; PF03776; MinE; 1.
DR   SUPFAM; SSF55229; SSF55229; 1.
DR   TIGRFAMs; TIGR01215; minE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division; Reference proteome.
FT   CHAIN           1..94
FT                   /note="Cell division topological specificity factor"
FT                   /id="PRO_1000204683"
SQ   SEQUENCE   94 AA;  10763 MW;  9D37FC7B02943411 CRC64;
     MGFFDFFSPD KKNSAANIAK DRLQIIVRER RCCDRDPLYL SDMKRDILAV ICKYVQLDPN
     ALHVQFEQKE DDVSVLELNV ILPEVSSTGD CSKP