ID   MINE_HELPJ              Reviewed;          77 AA.
AC   Q9ZMA7;
DT   11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-1999, sequence version 1.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Cell division topological specificity factor;
GN   Name=minE; OrderedLocusNames=jhp_0315;
OS   Helicobacter pylori (strain J99 / ATCC 700824) (Campylobacter pylori J99).
OC   Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales;
OC   Helicobacteraceae; Helicobacter.
OX   NCBI_TaxID=85963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=J99 / ATCC 700824;
RX   PubMed=9923682; DOI=10.1038/16495;
RA   Alm R.A., Ling L.-S.L., Moir D.T., King B.L., Brown E.D., Doig P.C.,
RA   Smith D.R., Noonan B., Guild B.C., deJonge B.L., Carmel G., Tummino P.J.,
RA   Caruso A., Uria-Nickelsen M., Mills D.M., Ives C., Gibson R., Merberg D.,
RA   Mills S.D., Jiang Q., Taylor D.E., Vovis G.F., Trust T.J.;
RT   "Genomic sequence comparison of two unrelated isolates of the human gastric
RT   pathogen Helicobacter pylori.";
RL   Nature 397:176-180(1999).
CC   -!- FUNCTION: Prevents the cell division inhibition by proteins MinC and
CC       MinD at internal division sites while permitting inhibition at polar
CC       sites. This ensures cell division at the proper site by restricting the
CC       formation of a division septum at the midpoint of the long axis of the
CC       cell (By similarity). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the MinE family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AE001439; AAD05906.1; -; Genomic_DNA.
DR   PIR; C71945; C71945.
DR   RefSeq; WP_000051412.1; NZ_CP011330.1.
DR   AlphaFoldDB; Q9ZMA7; -.
DR   SMR; Q9ZMA7; -.
DR   STRING; 85963.jhp_0315; -.
DR   EnsemblBacteria; AAD05906; AAD05906; jhp_0315.
DR   KEGG; hpj:jhp_0315; -.
DR   PATRIC; fig|85963.30.peg.698; -.
DR   eggNOG; COG0851; Bacteria.
DR   OMA; TIMLSHE; -.
DR   Proteomes; UP000000804; Chromosome.
DR   GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR   GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR   GO; GO:0032955; P:regulation of division septum assembly; IEA:InterPro.
DR   Gene3D; 3.30.1070.10; -; 1.
DR   HAMAP; MF_00262; MinE; 1.
DR   InterPro; IPR005527; MinE.
DR   InterPro; IPR036707; MinE_sf.
DR   Pfam; PF03776; MinE; 1.
DR   SUPFAM; SSF55229; SSF55229; 1.
DR   TIGRFAMs; TIGR01215; minE; 1.
PE   3: Inferred from homology;
KW   Cell cycle; Cell division.
FT   CHAIN           1..77
FT                   /note="Cell division topological specificity factor"
FT                   /id="PRO_0000205878"
SQ   SEQUENCE   77 AA;  8862 MW;  59B0A6E9A42651B6 CRC64;
     MSLFDFFKNK GSAATATDRL KLILAKERTL NLPYMEEMRK EIIAVIQKYT KSSDIHFKTL
     DGNQSVETIE VEIILPK