MINE_LACE2
ID MINE_LACE2 Reviewed; 91 AA.
AC C4Z090;
DT 22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Cell division topological specificity factor {ECO:0000255|HAMAP-Rule:MF_00262};
GN Name=minE {ECO:0000255|HAMAP-Rule:MF_00262};
GN OrderedLocusNames=EUBELI_01002;
OS Lachnospira eligens (strain ATCC 27750 / DSM 3376 / VPI C15-48 / C15-B4)
OS (Eubacterium eligens).
OC Bacteria; Firmicutes; Clostridia; Eubacteriales; Lachnospiraceae;
OC Lachnospira.
OX NCBI_TaxID=515620;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 27750 / DSM 3376 / VPI C15-48 / C15-B4;
RX PubMed=19321416; DOI=10.1073/pnas.0901529106;
RA Mahowald M.A., Rey F.E., Seedorf H., Turnbaugh P.J., Fulton R.S.,
RA Wollam A., Shah N., Wang C., Magrini V., Wilson R.K., Cantarel B.L.,
RA Coutinho P.M., Henrissat B., Crock L.W., Russell A., Verberkmoes N.C.,
RA Hettich R.L., Gordon J.I.;
RT "Characterizing a model human gut microbiota composed of members of its two
RT dominant bacterial phyla.";
RL Proc. Natl. Acad. Sci. U.S.A. 106:5859-5864(2009).
CC -!- FUNCTION: Prevents the cell division inhibition by proteins MinC and
CC MinD at internal division sites while permitting inhibition at polar
CC sites. This ensures cell division at the proper site by restricting the
CC formation of a division septum at the midpoint of the long axis of the
CC cell. {ECO:0000255|HAMAP-Rule:MF_00262}.
CC -!- SIMILARITY: Belongs to the MinE family. {ECO:0000255|HAMAP-
CC Rule:MF_00262}.
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DR EMBL; CP001104; ACR72003.1; -; Genomic_DNA.
DR RefSeq; WP_012739238.1; NC_012778.1.
DR AlphaFoldDB; C4Z090; -.
DR STRING; 515620.EUBELI_01002; -.
DR EnsemblBacteria; ACR72003; ACR72003; EUBELI_01002.
DR GeneID; 41355730; -.
DR KEGG; eel:EUBELI_01002; -.
DR eggNOG; COG0851; Bacteria.
DR HOGENOM; CLU_137929_1_0_9; -.
DR OMA; VHDRANV; -.
DR OrthoDB; 2038628at2; -.
DR Proteomes; UP000001476; Chromosome.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0032955; P:regulation of division septum assembly; IEA:InterPro.
DR Gene3D; 3.30.1070.10; -; 1.
DR HAMAP; MF_00262; MinE; 1.
DR InterPro; IPR005527; MinE.
DR InterPro; IPR036707; MinE_sf.
DR Pfam; PF03776; MinE; 1.
DR SUPFAM; SSF55229; SSF55229; 1.
DR TIGRFAMs; TIGR01215; minE; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Reference proteome.
FT CHAIN 1..91
FT /note="Cell division topological specificity factor"
FT /id="PRO_1000204681"
SQ SEQUENCE 91 AA; 10119 MW; C5D18FE0ED8A067E CRC64;
MGLLDLFKKK GSSDVAKDRL KLLLVSDRAN CSPEVMEMIK NDIIKVISKY MEIDTDGLDI
QITSTESDTN NGSVPAIFAN IPIKDMRNSE K