MINE_NEIMB
ID MINE_NEIMB Reviewed; 87 AA.
AC Q9K1H9;
DT 11-JAN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2000, sequence version 1.
DT 25-MAY-2022, entry version 93.
DE RecName: Full=Cell division topological specificity factor;
GN Name=minE; OrderedLocusNames=NMB0172;
OS Neisseria meningitidis serogroup B (strain MC58).
OC Bacteria; Proteobacteria; Betaproteobacteria; Neisseriales; Neisseriaceae;
OC Neisseria.
OX NCBI_TaxID=122586;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MC58;
RX PubMed=10710307; DOI=10.1126/science.287.5459.1809;
RA Tettelin H., Saunders N.J., Heidelberg J.F., Jeffries A.C., Nelson K.E.,
RA Eisen J.A., Ketchum K.A., Hood D.W., Peden J.F., Dodson R.J., Nelson W.C.,
RA Gwinn M.L., DeBoy R.T., Peterson J.D., Hickey E.K., Haft D.H.,
RA Salzberg S.L., White O., Fleischmann R.D., Dougherty B.A., Mason T.M.,
RA Ciecko A., Parksey D.S., Blair E., Cittone H., Clark E.B., Cotton M.D.,
RA Utterback T.R., Khouri H.M., Qin H., Vamathevan J.J., Gill J., Scarlato V.,
RA Masignani V., Pizza M., Grandi G., Sun L., Smith H.O., Fraser C.M.,
RA Moxon E.R., Rappuoli R., Venter J.C.;
RT "Complete genome sequence of Neisseria meningitidis serogroup B strain
RT MC58.";
RL Science 287:1809-1815(2000).
CC -!- FUNCTION: Prevents the cell division inhibition by proteins MinC and
CC MinD at internal division sites while permitting inhibition at polar
CC sites. This ensures cell division at the proper site by restricting the
CC formation of a division septum at the midpoint of the long axis of the
CC cell (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MinE family. {ECO:0000305}.
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DR EMBL; AE002098; AAF40629.1; -; Genomic_DNA.
DR PIR; D81230; D81230.
DR RefSeq; NP_273230.1; NC_003112.2.
DR RefSeq; WP_002215465.1; NC_003112.2.
DR AlphaFoldDB; Q9K1H9; -.
DR SMR; Q9K1H9; -.
DR STRING; 122586.NMB0172; -.
DR PaxDb; Q9K1H9; -.
DR EnsemblBacteria; AAF40629; AAF40629; NMB0172.
DR KEGG; nme:NMB0172; -.
DR PATRIC; fig|122586.8.peg.213; -.
DR HOGENOM; CLU_137929_2_1_4; -.
DR OMA; QIIVARE; -.
DR Proteomes; UP000000425; Chromosome.
DR GO; GO:0005886; C:plasma membrane; IBA:GO_Central.
DR GO; GO:0000918; P:division septum site selection; IBA:GO_Central.
DR GO; GO:0032955; P:regulation of division septum assembly; IBA:GO_Central.
DR Gene3D; 3.30.1070.10; -; 1.
DR HAMAP; MF_00262; MinE; 1.
DR InterPro; IPR005527; MinE.
DR InterPro; IPR036707; MinE_sf.
DR Pfam; PF03776; MinE; 1.
DR SUPFAM; SSF55229; SSF55229; 1.
DR TIGRFAMs; TIGR01215; minE; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Reference proteome.
FT CHAIN 1..87
FT /note="Cell division topological specificity factor"
FT /id="PRO_0000205881"
SQ SEQUENCE 87 AA; 10045 MW; AF57460A9C3FF013 CRC64;
MSLIEFLFGR KQKTATVARD RLQIIIAQER AQEGQAPDYL PTLRKELMEV LSKYVNVSLD
NIRISQEKQD GMDVLELNIT LPEQKKV