MINE_SHIFL
ID MINE_SHIFL Reviewed; 88 AA.
AC P0A737; P18198;
DT 07-JUN-2005, integrated into UniProtKB/Swiss-Prot.
DT 07-JUN-2005, sequence version 1.
DT 25-MAY-2022, entry version 87.
DE RecName: Full=Cell division topological specificity factor;
GN Name=minE; OrderedLocusNames=SF1161, S1247;
OS Shigella flexneri.
OC Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC Enterobacteriaceae; Shigella.
OX NCBI_TaxID=623;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=301 / Serotype 2a;
RX PubMed=12384590; DOI=10.1093/nar/gkf566;
RA Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT through comparison with genomes of Escherichia coli K12 and O157.";
RL Nucleic Acids Res. 30:4432-4441(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT "Complete genome sequence and comparative genomics of Shigella flexneri
RT serotype 2a strain 2457T.";
RL Infect. Immun. 71:2775-2786(2003).
CC -!- FUNCTION: Prevents the cell division inhibition by proteins MinC and
CC MinD at internal division sites while permitting inhibition at polar
CC sites. This ensures cell division at the proper site by restricting the
CC formation of a division septum at the midpoint of the long axis of the
CC cell (By similarity). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the MinE family. {ECO:0000305}.
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DR EMBL; AE005674; AAN42777.1; -; Genomic_DNA.
DR EMBL; AE014073; AAP16669.1; -; Genomic_DNA.
DR RefSeq; NP_707070.1; NC_004337.2.
DR RefSeq; WP_001185665.1; NZ_WPGW01000222.1.
DR AlphaFoldDB; P0A737; -.
DR SMR; P0A737; -.
DR STRING; 198214.SF1161; -.
DR PRIDE; P0A737; -.
DR EnsemblBacteria; AAN42777; AAN42777; SF1161.
DR EnsemblBacteria; AAP16669; AAP16669; S1247.
DR GeneID; 1024127; -.
DR GeneID; 67415436; -.
DR KEGG; sfl:SF1161; -.
DR KEGG; sfx:S1247; -.
DR PATRIC; fig|198214.7.peg.1371; -.
DR HOGENOM; CLU_137929_2_2_6; -.
DR OMA; QIIVARE; -.
DR OrthoDB; 2038628at2; -.
DR Proteomes; UP000001006; Chromosome.
DR Proteomes; UP000002673; Chromosome.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0032955; P:regulation of division septum assembly; IEA:InterPro.
DR Gene3D; 3.30.1070.10; -; 1.
DR HAMAP; MF_00262; MinE; 1.
DR InterPro; IPR005527; MinE.
DR InterPro; IPR036707; MinE_sf.
DR Pfam; PF03776; MinE; 1.
DR SUPFAM; SSF55229; SSF55229; 1.
DR TIGRFAMs; TIGR01215; minE; 1.
PE 3: Inferred from homology;
KW Cell cycle; Cell division; Reference proteome.
FT CHAIN 1..88
FT /note="Cell division topological specificity factor"
FT /id="PRO_0000205888"
SQ SEQUENCE 88 AA; 10235 MW; 04DDFB4EA24F96C1 CRC64;
MALLDFFLSR KKNTANIAKE RLQIIVAERR RSDAEPHYLP QLRKDILEVI CKYVQIDPEM
VTVQLEQKDG DISILELNVT LPEAEELK