ID   6PGL_BLOPB              Reviewed;         337 AA.
AC   Q492W6;
DT   12-JUN-2007, integrated into UniProtKB/Swiss-Prot.
DT   13-SEP-2005, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=6-phosphogluconolactonase {ECO:0000255|HAMAP-Rule:MF_01605};
DE            Short=6-P-gluconolactonase {ECO:0000255|HAMAP-Rule:MF_01605};
DE            EC=3.1.1.31 {ECO:0000255|HAMAP-Rule:MF_01605};
GN   Name=pgl {ECO:0000255|HAMAP-Rule:MF_01605}; OrderedLocusNames=BPEN_351;
OS   Blochmannia pennsylvanicus (strain BPEN).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; ant endosymbionts; Candidatus Blochmannia.
OX   NCBI_TaxID=291272;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=BPEN;
RX   PubMed=16077009; DOI=10.1101/gr.3771305;
RA   Degnan P.H., Lazarus A.B., Wernegreen J.J.;
RT   "Genome sequence of Blochmannia pennsylvanicus indicates parallel
RT   evolutionary trends among bacterial mutualists of insects.";
RL   Genome Res. 15:1023-1033(2005).
CC   -!- FUNCTION: Catalyzes the hydrolysis of 6-phosphogluconolactone to 6-
CC       phosphogluconate. {ECO:0000255|HAMAP-Rule:MF_01605}.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=6-phospho-D-glucono-1,5-lactone + H2O = 6-phospho-D-gluconate
CC         + H(+); Xref=Rhea:RHEA:12556, ChEBI:CHEBI:15377, ChEBI:CHEBI:15378,
CC         ChEBI:CHEBI:57955, ChEBI:CHEBI:58759; EC=3.1.1.31;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_01605};
CC   -!- PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-
CC       ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step
CC       2/3. {ECO:0000255|HAMAP-Rule:MF_01605}.
CC   -!- SIMILARITY: Belongs to the cycloisomerase 2 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01605}.
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DR   EMBL; CP000016; AAZ40976.1; -; Genomic_DNA.
DR   RefSeq; WP_011282885.1; NC_007292.1.
DR   AlphaFoldDB; Q492W6; -.
DR   SMR; Q492W6; -.
DR   STRING; 291272.BPEN_351; -.
DR   EnsemblBacteria; AAZ40976; AAZ40976; BPEN_351.
DR   KEGG; bpn:BPEN_351; -.
DR   eggNOG; COG2706; Bacteria.
DR   HOGENOM; CLU_038716_2_0_6; -.
DR   OMA; EGNWPRD; -.
DR   BioCyc; CBLO291272:BPEN_RS01725-MON; -.
DR   UniPathway; UPA00115; UER00409.
DR   Proteomes; UP000007794; Chromosome.
DR   GO; GO:0017057; F:6-phosphogluconolactonase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:UniProtKB-UniPathway.
DR   Gene3D; 2.130.10.10; -; 1.
DR   HAMAP; MF_01605; 6P_gluconolactonase; 1.
DR   InterPro; IPR022528; 6-phosphogluconolactonase_YbhE.
DR   InterPro; IPR019405; Lactonase_7-beta_prop.
DR   InterPro; IPR011045; N2O_reductase_N.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   Pfam; PF10282; Lactonase; 1.
DR   SUPFAM; SSF50974; SSF50974; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Glucose metabolism; Hydrolase.
FT   CHAIN           1..337
FT                   /note="6-phosphogluconolactonase"
FT                   /id="PRO_0000291464"
SQ   SEQUENCE   337 AA;  37952 MW;  C244FCF464675BF3 CRC64;
     MIQIIYVASP ESQQIHVWKL DSIYGLLELI QVIYTHGQAQ PMAVHPNKRF LYVGIRPNFG
     ITTYRIDQIG LLADHGTIGI FSSPTHLISD KKGAFLYCTS YRNNTVSVIP ISMSGMLLDS
     PIQIIEGLLG CHSANIDKFK KLLWVPCLKE NAIRLFNINS FGMLTSYDPS IIKINVGSGP
     RHMIFCDFDC YAYVINELTS TVDVIKYNNF QKIPSIVQTV SIIPKNISIN RCWAADIHIT
     PNGRWLYCTD RSINIISCLE ISKKTKKLKF VGYQLTEEQP RGFAIDYQGK FLVVAGQKSN
     CISLYKIDSD NGTLTMLSRY SSGKGPMWVS IITLNCK