ID   MIP1_ARATH              Reviewed;         711 AA.
AC   Q8RX22; Q9C7Y6; Q9LQK4;
DT   16-JUN-2009, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 120.
DE   RecName: Full=MND1-interacting protein 1;
DE            Short=AtMIP1;
GN   Name=MIP1; OrderedLocusNames=At1g32530; ORFNames=F5D14.31, T9G5.5;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   INTERACTION WITH MND1; HOP2 AND XRI1.
RX   PubMed=19187040; DOI=10.1111/j.1365-313x.2009.03814.x;
RA   Dean P.J., Siwiec T., Waterworth W.M., Schloegelhofer P., Armstrong S.J.,
RA   West C.E.;
RT   "A novel ATM dependant X-ray inducible gene is essential for both plant
RT   meiosis and gametogenesis.";
RL   Plant J. 58:791-802(2009).
CC   -!- SUBUNIT: Interacts (via C-terminal domain) with MND1 and HOP2.
CC       Interacts with XRI1 (via C-terminal domain).
CC       {ECO:0000269|PubMed:19187040}.
CC   -!- INTERACTION:
CC       Q8RX22; Q8GYD2: MND1; NbExp=2; IntAct=EBI-2270543, EBI-1554720;
CC       Q8RX22; Q6NLW5: XRI1; NbExp=2; IntAct=EBI-2270543, EBI-2270660;
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF81351.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC007767; AAF81351.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AC055769; AAG51242.1; -; Genomic_DNA.
DR   EMBL; CP002684; AEE31497.1; -; Genomic_DNA.
DR   EMBL; AY090954; AAM14000.1; -; mRNA.
DR   EMBL; AY133855; AAM91789.1; -; mRNA.
DR   PIR; G86450; G86450.
DR   RefSeq; NP_174531.1; NM_102988.5.
DR   AlphaFoldDB; Q8RX22; -.
DR   SMR; Q8RX22; -.
DR   BioGRID; 25381; 4.
DR   DIP; DIP-54876N; -.
DR   IntAct; Q8RX22; 4.
DR   STRING; 3702.AT1G32530.1; -.
DR   iPTMnet; Q8RX22; -.
DR   PaxDb; Q8RX22; -.
DR   PRIDE; Q8RX22; -.
DR   ProteomicsDB; 237114; -.
DR   EnsemblPlants; AT1G32530.1; AT1G32530.1; AT1G32530.
DR   GeneID; 840147; -.
DR   Gramene; AT1G32530.1; AT1G32530.1; AT1G32530.
DR   KEGG; ath:AT1G32530; -.
DR   Araport; AT1G32530; -.
DR   TAIR; locus:2033765; AT1G32530.
DR   eggNOG; ENOG502QVIE; Eukaryota.
DR   HOGENOM; CLU_012143_0_0_1; -.
DR   InParanoid; Q8RX22; -.
DR   OMA; SEKEINC; -.
DR   OrthoDB; 998412at2759; -.
DR   PhylomeDB; Q8RX22; -.
DR   PRO; PR:Q8RX22; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q8RX22; baseline and differential.
DR   Genevisible; Q8RX22; AT.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.40.10; -; 1.
DR   InterPro; IPR001841; Znf_RING.
DR   InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR   PROSITE; PS50089; ZF_RING_2; 1.
PE   1: Evidence at protein level;
KW   Coiled coil; Metal-binding; Reference proteome; Zinc; Zinc-finger.
FT   CHAIN           1..711
FT                   /note="MND1-interacting protein 1"
FT                   /id="PRO_0000376837"
FT   ZN_FING         653..697
FT                   /note="RING-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00175"
FT   REGION          552..571
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          602..622
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          390..648
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        607..622
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   711 AA;  79328 MW;  1DDF44ADFBCC975F CRC64;
     MGCTVREKHV KPTRRIKAAA FRSDPPLCWV EKIAMSQSIV ENLVYHPGLT DSGSVNLNSV
     TENPEENFWA YCTEEHLEEI LLKHLEFLYN QAVSKLLELG YEERVALKAV LSNGHCYGEL
     DVLTNIVNNS LSYLNSGGGG GGSNGNGEDR TETGFTDLRD LEEYSLAGMI YLLQQVKPNL
     SKGDAMWCLL MSELHVGRAS TLDVPTNRSS CCTKEDSNVE DVGTGGTLDI AGFMAPALCR
     FHGGWGFGNG GGPEFSGNGF SMKGAELKLQ REIDCPKRFN LSPSMKSLLK RNVAAFAAGY
     RASMKQKQIQ SSDTIGDSKA CNDPAIVKSC GQQPRKSGSE ESVSTVLEKF RDLNLDDNLE
     SVGVDDKDCV IVDLLHQVKD FEKKVKERKE WAQKNAMQAA QKVSEELAEL KTLSSEREGI
     QLLKKGKQAV EESTAKRFTD KEIELRKACS QNDRANVIVR KLENQNAEIR AEREGSKLSA
     SESLKACMEA SKKEKKCLKK LVAWEKQILK LQDEITAEKE KIKALYKTLA QITEYEKEIE
     AKWRQEQKAK EEALAQMEEE QRSKEAAEGH NKRKLETLRL KIELDFQRHK DDHQRLEQEL
     GRLKASSDSD SSHISNNAWK PKKSQGENIA KLLEEIDKLE GSYDNEANYD RECIICMKDE
     VSVVFLPCAH QVVCGSCSDS FFASNNGGSK VTCPCCRGLV QQRIRIFGAT S