ID   MIPA_SHIFL              Reviewed;         248 AA.
AC   P0A909; O07962; P77486;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2005, sequence version 1.
DT   25-MAY-2022, entry version 94.
DE   RecName: Full=MltA-interacting protein;
DE   Flags: Precursor;
GN   Name=mipA; OrderedLocusNames=SF1441, S1556;
OS   Shigella flexneri.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Shigella.
OX   NCBI_TaxID=623;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=301 / Serotype 2a;
RX   PubMed=12384590; DOI=10.1093/nar/gkf566;
RA   Jin Q., Yuan Z., Xu J., Wang Y., Shen Y., Lu W., Wang J., Liu H., Yang J.,
RA   Yang F., Zhang X., Zhang J., Yang G., Wu H., Qu D., Dong J., Sun L.,
RA   Xue Y., Zhao A., Gao Y., Zhu J., Kan B., Ding K., Chen S., Cheng H.,
RA   Yao Z., He B., Chen R., Ma D., Qiang B., Wen Y., Hou Y., Yu J.;
RT   "Genome sequence of Shigella flexneri 2a: insights into pathogenicity
RT   through comparison with genomes of Escherichia coli K12 and O157.";
RL   Nucleic Acids Res. 30:4432-4441(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700930 / 2457T / Serotype 2a;
RX   PubMed=12704152; DOI=10.1128/iai.71.5.2775-2786.2003;
RA   Wei J., Goldberg M.B., Burland V., Venkatesan M.M., Deng W., Fournier G.,
RA   Mayhew G.F., Plunkett G. III, Rose D.J., Darling A., Mau B., Perna N.T.,
RA   Payne S.M., Runyen-Janecky L.J., Zhou S., Schwartz D.C., Blattner F.R.;
RT   "Complete genome sequence and comparative genomics of Shigella flexneri
RT   serotype 2a strain 2457T.";
RL   Infect. Immun. 71:2775-2786(2003).
CC   -!- FUNCTION: May serve as a scaffold protein required for the formation of
CC       a complex with MrcB/PonB and MltA, this complex could play a role in
CC       enlargement and septation of the murein sacculus. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the MipA/OmpV family. {ECO:0000305}.
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DR   EMBL; AE005674; AAN43039.1; -; Genomic_DNA.
DR   EMBL; AE014073; AAP16934.1; -; Genomic_DNA.
DR   RefSeq; NP_707332.1; NC_004337.2.
DR   RefSeq; WP_000163771.1; NZ_UIQL01000057.1.
DR   AlphaFoldDB; P0A909; -.
DR   STRING; 198214.SF1441; -.
DR   DNASU; 1080449; -.
DR   EnsemblBacteria; AAN43039; AAN43039; SF1441.
DR   EnsemblBacteria; AAP16934; AAP16934; S1556.
DR   GeneID; 1024630; -.
DR   GeneID; 58391373; -.
DR   KEGG; sfl:SF1441; -.
DR   KEGG; sfx:S1556; -.
DR   PATRIC; fig|198214.7.peg.1697; -.
DR   HOGENOM; CLU_063465_3_0_6; -.
DR   OMA; EVKDSPM; -.
DR   OrthoDB; 1497770at2; -.
DR   Proteomes; UP000001006; Chromosome.
DR   Proteomes; UP000002673; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   InterPro; IPR010583; MipA.
DR   PANTHER; PTHR38776; PTHR38776; 1.
DR   Pfam; PF06629; MipA; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Membrane; Reference proteome; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000250"
FT   CHAIN           23..248
FT                   /note="MltA-interacting protein"
FT                   /id="PRO_0000019093"
SQ   SEQUENCE   248 AA;  27831 MW;  6571B0D7A47A0525 CRC64;
     MTKLKLLALG VLIATSAGVA HAEGKFSLGA GVGVVEHPYK DYDTDVYPVP VINYEGDNFW
     FRGLGGGYYL WNDATDKLSI TAYWSPLYFK AKDSGDHQMR HLDDRKSTMM AGLSYAHFTQ
     YGYLRTTLAG DTLDNSNGIV WDMAWLYRYT NGGLTVTPGI GVQWNSENQN EYYYGVSRKE
     SARSGLRGYN PNDSWSPYLE LSASYNFLGD WSVYGTARYT RLSDEVTDSP MVDKSWTGLI
     STGITYKF