ID   MIPO1_MOUSE             Reviewed;         279 AA.
AC   Q9D9F8;
DT   01-MAR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   25-MAY-2022, entry version 77.
DE   RecName: Full=Mirror-image polydactyly gene 1 protein homolog;
GN   Name=Mipol1;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Testis;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [2]
RP   DEVELOPMENTAL STAGE.
RX   PubMed=11954550; DOI=10.1007/s100380200015;
RA   Kondoh S., Sugawara H., Harada N., Matsumoto N., Ohashi H., Sato M.,
RA   Kantaputra P.N., Ogino T., Tomita H., Ohta T., Kishino T., Fukushima Y.,
RA   Niikawa N., Yoshiura K.;
RT   "A novel gene is disrupted at a 14q13 breakpoint of t(2;14) in a patient
RT   with mirror-image polydactyly of hands and feet.";
RL   J. Hum. Genet. 47:136-139(2002).
CC   -!- DEVELOPMENTAL STAGE: Expressed in embryo between 10.5 and 13.5 dpc.
CC       {ECO:0000269|PubMed:11954550}.
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DR   EMBL; AK006974; BAB24815.1; -; mRNA.
DR   AlphaFoldDB; Q9D9F8; -.
DR   SMR; Q9D9F8; -.
DR   STRING; 10090.ENSMUSP00000121617; -.
DR   PRIDE; Q9D9F8; -.
DR   ProteomicsDB; 252567; -.
DR   MGI; MGI:1920740; Mipol1.
DR   eggNOG; ENOG502QS3V; Eukaryota.
DR   InParanoid; Q9D9F8; -.
DR   ChiTaRS; Mipol1; mouse.
DR   PRO; PR:Q9D9F8; -.
DR   Proteomes; UP000000589; Unplaced.
DR   RNAct; Q9D9F8; protein.
DR   GO; GO:0005634; C:nucleus; ISO:MGI.
DR   GO; GO:0042802; F:identical protein binding; ISO:MGI.
DR   InterPro; IPR026175; MIPOL1.
DR   PANTHER; PTHR22089; PTHR22089; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..279
FT                   /note="Mirror-image polydactyly gene 1 protein homolog"
FT                   /id="PRO_0000096491"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          247..268
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          65..169
FT                   /evidence="ECO:0000255"
FT   COILED          218..255
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   279 AA;  31751 MW;  CBCD185A98A96987 CRC64;
     MNSEQSIREL GNEVPSEDLE LPGRKTSNFQ VLQPCRDEGA SAECSIVECG KNYEPVISHQ
     VIPDLNKETS VAYLQKELEI LRASNTKLQE KLAKEDKEKR RLKLKLELQE KAAEADIAER
     TAALVEEVYF AQRERDEAIM CRLQLALKER DEAIAHVKHM EMSLKMLENI NPKENDMTLQ
     ELLDRINNAD TGIAIQKNGA VIVDTIYKTT GCRKRITAEE MSAVLEERDA ALSQCKQLHQ
     RLLDLKKQNQ TSTNNTKHPT AKNNQEHTLK YNLNIASIN