MISSL_MOUSE
ID MISSL_MOUSE Reviewed; 242 AA.
AC Q8BH93; Q3TF12; Q3TGL0; Q8CC90;
DT 11-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT 23-JAN-2007, sequence version 3.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=MAPK-interacting and spindle-stabilizing protein-like;
DE AltName: Full=Mitogen-activated protein kinase 1-interacting protein 1-like;
GN Name=Mapk1ip1l;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Amnion, Cecum, Embryo, Embryonic head, and Lung;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=FVB/N; TISSUE=Colon;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- SIMILARITY: Belongs to the MISS family. {ECO:0000305}.
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DR EMBL; AK033615; BAC28392.1; -; mRNA.
DR EMBL; AK048061; BAC33228.1; -; mRNA.
DR EMBL; AK086896; BAC39759.1; -; mRNA.
DR EMBL; AK143495; BAE25398.1; -; mRNA.
DR EMBL; AK168694; BAE40538.1; -; mRNA.
DR EMBL; AK169333; BAE41086.1; -; mRNA.
DR EMBL; BC047201; AAH47201.1; -; mRNA.
DR CCDS; CCDS49469.1; -.
DR RefSeq; NP_848799.1; NM_178684.5.
DR AlphaFoldDB; Q8BH93; -.
DR BioGRID; 230089; 2.
DR STRING; 10090.ENSMUSP00000132875; -.
DR iPTMnet; Q8BH93; -.
DR PhosphoSitePlus; Q8BH93; -.
DR EPD; Q8BH93; -.
DR MaxQB; Q8BH93; -.
DR PaxDb; Q8BH93; -.
DR PeptideAtlas; Q8BH93; -.
DR PRIDE; Q8BH93; -.
DR ProteomicsDB; 295618; -.
DR Ensembl; ENSMUST00000164235; ENSMUSP00000132875; ENSMUSG00000021840.
DR Ensembl; ENSMUST00000166743; ENSMUSP00000127475; ENSMUSG00000021840.
DR GeneID; 218975; -.
DR KEGG; mmu:218975; -.
DR UCSC; uc007thy.1; mouse.
DR CTD; 93487; -.
DR MGI; MGI:2444022; Mapk1ip1l.
DR VEuPathDB; HostDB:ENSMUSG00000021840; -.
DR eggNOG; ENOG502RYAB; Eukaryota.
DR GeneTree; ENSGT00730000111340; -.
DR HOGENOM; CLU_063887_0_0_1; -.
DR InParanoid; Q8BH93; -.
DR OMA; PWNTPSA; -.
DR OrthoDB; 1455063at2759; -.
DR PhylomeDB; Q8BH93; -.
DR BioGRID-ORCS; 218975; 9 hits in 72 CRISPR screens.
DR ChiTaRS; Mapk1ip1l; mouse.
DR PRO; PR:Q8BH93; -.
DR Proteomes; UP000000589; Chromosome 14.
DR RNAct; Q8BH93; protein.
DR Bgee; ENSMUSG00000021840; Expressed in manus and 224 other tissues.
DR ExpressionAtlas; Q8BH93; baseline and differential.
DR Genevisible; Q8BH93; MM.
DR InterPro; IPR031653; MISS.
DR PANTHER; PTHR35973; PTHR35973; 1.
DR Pfam; PF15822; MISS; 1.
PE 2: Evidence at transcript level;
KW Acetylation; Phosphoprotein; Reference proteome.
FT INIT_MET 1
FT /note="Removed"
FT /evidence="ECO:0000250|UniProtKB:Q8NDC0"
FT CHAIN 2..242
FT /note="MAPK-interacting and spindle-stabilizing protein-
FT like"
FT /id="PRO_0000209892"
FT REGION 1..145
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 192..242
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 17..39
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 40..54
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 70..132
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..235
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT MOD_RES 2
FT /note="N-acetylserine"
FT /evidence="ECO:0000250|UniProtKB:Q8NDC0"
FT MOD_RES 2
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8NDC0"
FT MOD_RES 6
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8NDC0"
FT MOD_RES 15
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q8NDC0"
FT CONFLICT 200
FT /note="A -> T (in Ref. 1; BAE40538)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 242 AA; 23885 MW; 3E9989AAAF780BC9 CRC64;
MSDEFSLADA LPEQSSAKPP AVTNTKAGHS SQGWPGSSPW SNPSAPPAMP SGLPPSSAAP
STVPFGPVPT GMYPSMPPTG PPPGPPGPFP PPGPSCPPPG VPYPAPAVPG PGPTGPYATP
NMPMPELPRP YGAPTDPAAA GSLGPWGPMS SGPWAPGIAG QHPNMPYRSP GPYPTVPPPV
SGAPPVPWGT VPPGAWGPAA PYPGPAGSYP TPAPHPALNN PYQVPSGPAG APPMPGGPHS
YH
