MK1_PALPR
ID MK1_PALPR Reviewed; 15 AA.
AC P80408;
DT 01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1995, sequence version 1.
DT 11-DEC-2019, entry version 47.
DE RecName: Full=Metalnikowin-1;
DE AltName: Full=Metalnikowin I;
OS Palomena prasina (Green shield bug) (Cimex prasinus).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Paraneoptera; Hemiptera; Heteroptera; Panheteroptera;
OC Pentatomomorpha; Pentatomoidea; Pentatomidae; Pentatominae; Palomena.
OX NCBI_TaxID=55431;
RN [1]
RP PROTEIN SEQUENCE, FUNCTION, INDUCTION, AND MASS SPECTROMETRY.
RC TISSUE=Hemolymph, and Larval hemolymph;
RX DOI=10.1016/0022-1910(95)00085-2;
RA Chernysh S., Cociancich S., Briand J.-P., Hetru C., Bulet P.;
RT "The inducible antibacterial peptides of the hemipteran insect Palomena
RT prasina: identification of a unique family of proline-rich peptides and of
RT a novel insect defensin.";
RL J. Insect Physiol. 42:81-89(1996).
CC -!- FUNCTION: Antibacterial peptide active against Gram-negative bacteria.
CC {ECO:0000269|Ref.1}.
CC -!- INDUCTION: By bacterial infection. {ECO:0000269|Ref.1}.
CC -!- MASS SPECTROMETRY: Mass=1838.6; Mass_error=0.7; Method=Electrospray;
CC Evidence={ECO:0000269|Ref.1};
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DR PDB; 5HCP; X-ray; 2.89 A; 1z/2z=1-15.
DR PDBsum; 5HCP; -.
DR SMR; P80408; -.
DR GO; GO:0005576; C:extracellular region; IDA:UniProtKB.
DR GO; GO:0050829; P:defense response to Gram-negative bacterium; IDA:UniProtKB.
DR GO; GO:0045087; P:innate immune response; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW 3D-structure; Antibiotic; Antimicrobial; Direct protein sequencing;
KW Immunity; Innate immunity.
FT PEPTIDE 1..15
FT /note="Metalnikowin-1"
FT /id="PRO_0000044160"
SQ SEQUENCE 15 AA; 1838 MW; 21407E663CE46299 CRC64;
VDKPDYRPRP RPPNM