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MK67I_XENTR
ID   MK67I_XENTR             Reviewed;         276 AA.
AC   Q6GL69;
DT   19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 92.
DE   RecName: Full=MKI67 FHA domain-interacting nucleolar phosphoprotein-like;
GN   Name=nifk; Synonyms=mki67ipl;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
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DR   EMBL; BC074637; AAH74637.1; -; mRNA.
DR   RefSeq; NP_001005639.1; NM_001005639.1.
DR   AlphaFoldDB; Q6GL69; -.
DR   SMR; Q6GL69; -.
DR   DNASU; 448106; -.
DR   GeneID; 448106; -.
DR   KEGG; xtr:448106; -.
DR   CTD; 84365; -.
DR   Xenbase; XB-GENE-940532; nifk.
DR   InParanoid; Q6GL69; -.
DR   OrthoDB; 1513142at2759; -.
DR   Proteomes; UP000008143; Chromosome 9.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR   Gene3D; 3.30.70.330; -; 1.
DR   InterPro; IPR021043; NIFK_FHA_Ki67-binding.
DR   InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR   InterPro; IPR035979; RBD_domain_sf.
DR   InterPro; IPR000504; RRM_dom.
DR   Pfam; PF12196; hNIFK_binding; 1.
DR   Pfam; PF00076; RRM_1; 1.
DR   SMART; SM00360; RRM; 1.
DR   SUPFAM; SSF54928; SSF54928; 1.
DR   PROSITE; PS50102; RRM; 1.
PE   2: Evidence at transcript level;
KW   Nucleus; Reference proteome; RNA-binding.
FT   CHAIN           1..276
FT                   /note="MKI67 FHA domain-interacting nucleolar
FT                   phosphoprotein-like"
FT                   /id="PRO_0000081633"
FT   DOMAIN          41..119
FT                   /note="RRM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT   REGION          190..211
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          256..276
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   276 AA;  31723 MW;  E339666DD39B5EA6 CRC64;
     MAEESVPSGS LLSLDPELQK DFQQKVHEIR RKSQVGAVSP GVIYIGHIPR ALYEPQLREY
     FSQFGTVTRL RLSRSKKTGN SKGYAYVEFE CDEVAKIVAD TMNNYLFCER LLKCEFVPPE
     KVHPRLFIGC TAKFRKPTKP AVSRYNKRRS EAEQKKMTQR MLSKENKVRK RLAEKGIDYD
     FPGFAARRER KEPTCDADTS VSSQDPTPVC TPTVLERRKS VRLEQNDEDD DDGEVVLKLP
     QEDEEVVLKL PLKVTPTAKR QKISKSEKKT KIKKQK
 
 
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