MK67I_XENTR
ID MK67I_XENTR Reviewed; 276 AA.
AC Q6GL69;
DT 19-JUL-2005, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 92.
DE RecName: Full=MKI67 FHA domain-interacting nucleolar phosphoprotein-like;
GN Name=nifk; Synonyms=mki67ipl;
OS Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX NCBI_TaxID=8364;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus, nucleolus {ECO:0000250}.
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DR EMBL; BC074637; AAH74637.1; -; mRNA.
DR RefSeq; NP_001005639.1; NM_001005639.1.
DR AlphaFoldDB; Q6GL69; -.
DR SMR; Q6GL69; -.
DR DNASU; 448106; -.
DR GeneID; 448106; -.
DR KEGG; xtr:448106; -.
DR CTD; 84365; -.
DR Xenbase; XB-GENE-940532; nifk.
DR InParanoid; Q6GL69; -.
DR OrthoDB; 1513142at2759; -.
DR Proteomes; UP000008143; Chromosome 9.
DR Proteomes; UP000790000; Unplaced.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR GO; GO:0000463; P:maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IBA:GO_Central.
DR Gene3D; 3.30.70.330; -; 1.
DR InterPro; IPR021043; NIFK_FHA_Ki67-binding.
DR InterPro; IPR012677; Nucleotide-bd_a/b_plait_sf.
DR InterPro; IPR035979; RBD_domain_sf.
DR InterPro; IPR000504; RRM_dom.
DR Pfam; PF12196; hNIFK_binding; 1.
DR Pfam; PF00076; RRM_1; 1.
DR SMART; SM00360; RRM; 1.
DR SUPFAM; SSF54928; SSF54928; 1.
DR PROSITE; PS50102; RRM; 1.
PE 2: Evidence at transcript level;
KW Nucleus; Reference proteome; RNA-binding.
FT CHAIN 1..276
FT /note="MKI67 FHA domain-interacting nucleolar
FT phosphoprotein-like"
FT /id="PRO_0000081633"
FT DOMAIN 41..119
FT /note="RRM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00176"
FT REGION 190..211
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 256..276
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 276 AA; 31723 MW; E339666DD39B5EA6 CRC64;
MAEESVPSGS LLSLDPELQK DFQQKVHEIR RKSQVGAVSP GVIYIGHIPR ALYEPQLREY
FSQFGTVTRL RLSRSKKTGN SKGYAYVEFE CDEVAKIVAD TMNNYLFCER LLKCEFVPPE
KVHPRLFIGC TAKFRKPTKP AVSRYNKRRS EAEQKKMTQR MLSKENKVRK RLAEKGIDYD
FPGFAARRER KEPTCDADTS VSSQDPTPVC TPTVLERRKS VRLEQNDEDD DDGEVVLKLP
QEDEEVVLKL PLKVTPTAKR QKISKSEKKT KIKKQK