ID   MKROS_HUMAN             Reviewed;         223 AA.
AC   H3BPM6;
DT   06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT   18-APR-2012, sequence version 1.
DT   03-AUG-2022, entry version 54.
DE   RecName: Full=MKRN2 opposite strand protein;
DE   AltName: Full=MKRN2 antisense RNA 1;
DE   AltName: Full=MKRN2 antisense gene protein 1;
GN   Name=MKRN2OS; Synonyms=C3orf83, MKRN2-AS1;
OS   Homo sapiens (Human).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC   Homo.
OX   NCBI_TaxID=9606;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16641997; DOI=10.1038/nature04728;
RA   Muzny D.M., Scherer S.E., Kaul R., Wang J., Yu J., Sudbrak R., Buhay C.J.,
RA   Chen R., Cree A., Ding Y., Dugan-Rocha S., Gill R., Gunaratne P.,
RA   Harris R.A., Hawes A.C., Hernandez J., Hodgson A.V., Hume J., Jackson A.,
RA   Khan Z.M., Kovar-Smith C., Lewis L.R., Lozado R.J., Metzker M.L.,
RA   Milosavljevic A., Miner G.R., Morgan M.B., Nazareth L.V., Scott G.,
RA   Sodergren E., Song X.-Z., Steffen D., Wei S., Wheeler D.A., Wright M.W.,
RA   Worley K.C., Yuan Y., Zhang Z., Adams C.Q., Ansari-Lari M.A., Ayele M.,
RA   Brown M.J., Chen G., Chen Z., Clendenning J., Clerc-Blankenburg K.P.,
RA   Chen R., Chen Z., Davis C., Delgado O., Dinh H.H., Dong W., Draper H.,
RA   Ernst S., Fu G., Gonzalez-Garay M.L., Garcia D.K., Gillett W., Gu J.,
RA   Hao B., Haugen E., Havlak P., He X., Hennig S., Hu S., Huang W.,
RA   Jackson L.R., Jacob L.S., Kelly S.H., Kube M., Levy R., Li Z., Liu B.,
RA   Liu J., Liu W., Lu J., Maheshwari M., Nguyen B.-V., Okwuonu G.O.,
RA   Palmeiri A., Pasternak S., Perez L.M., Phelps K.A., Plopper F.J., Qiang B.,
RA   Raymond C., Rodriguez R., Saenphimmachak C., Santibanez J., Shen H.,
RA   Shen Y., Subramanian S., Tabor P.E., Verduzco D., Waldron L., Wang J.,
RA   Wang J., Wang Q., Williams G.A., Wong G.K.-S., Yao Z., Zhang J., Zhang X.,
RA   Zhao G., Zhou J., Zhou Y., Nelson D., Lehrach H., Reinhardt R.,
RA   Naylor S.L., Yang H., Olson M., Weinstock G., Gibbs R.A.;
RT   "The DNA sequence, annotation and analysis of human chromosome 3.";
RL   Nature 440:1194-1198(2006).
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DR   EMBL; AC018500; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   CCDS; CCDS58816.1; -.
DR   RefSeq; NP_001182208.1; NM_001195279.1.
DR   AlphaFoldDB; H3BPM6; -.
DR   BioGRID; 934106; 1.
DR   STRING; 9606.ENSP00000455385; -.
DR   iPTMnet; H3BPM6; -.
DR   PhosphoSitePlus; H3BPM6; -.
DR   BioMuta; MKRN2OS; -.
DR   EPD; H3BPM6; -.
DR   MassIVE; H3BPM6; -.
DR   PaxDb; H3BPM6; -.
DR   PeptideAtlas; H3BPM6; -.
DR   PRIDE; H3BPM6; -.
DR   ProteomicsDB; 41538; -.
DR   Antibodypedia; 77123; 9 antibodies from 5 providers.
DR   DNASU; 100129480; -.
DR   Ensembl; ENST00000564146.4; ENSP00000455385.3; ENSG00000225526.6.
DR   GeneID; 100129480; -.
DR   KEGG; hsa:100129480; -.
DR   MANE-Select; ENST00000564146.4; ENSP00000455385.3; NM_001195279.2; NP_001182208.1.
DR   UCSC; uc021wtc.2; human.
DR   CTD; 100129480; -.
DR   DisGeNET; 100129480; -.
DR   GeneCards; MKRN2OS; -.
DR   HGNC; HGNC:40375; MKRN2OS.
DR   HPA; ENSG00000225526; Tissue enhanced (epididymis, intestine).
DR   neXtProt; NX_H3BPM6; -.
DR   OpenTargets; ENSG00000225526; -.
DR   VEuPathDB; HostDB:ENSG00000225526; -.
DR   eggNOG; ENOG502R8ZC; Eukaryota.
DR   GeneTree; ENSGT00390000003839; -.
DR   HOGENOM; CLU_084023_0_0_1; -.
DR   InParanoid; H3BPM6; -.
DR   OMA; HIGVTNS; -.
DR   OrthoDB; 1134473at2759; -.
DR   PhylomeDB; H3BPM6; -.
DR   TreeFam; TF323599; -.
DR   PathwayCommons; H3BPM6; -.
DR   SignaLink; H3BPM6; -.
DR   BioGRID-ORCS; 100129480; 15 hits in 1019 CRISPR screens.
DR   Pharos; H3BPM6; Tdark.
DR   PRO; PR:H3BPM6; -.
DR   Proteomes; UP000005640; Chromosome 3.
DR   RNAct; H3BPM6; protein.
DR   Bgee; ENSG00000225526; Expressed in cerebellum and 98 other tissues.
DR   ExpressionAtlas; H3BPM6; baseline and differential.
DR   InterPro; IPR032016; DUF4796.
DR   PANTHER; PTHR33963; PTHR33963; 1.
DR   Pfam; PF16044; DUF4796; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..223
FT                   /note="MKRN2 opposite strand protein"
FT                   /id="PRO_0000421254"
SQ   SEQUENCE   223 AA;  25451 MW;  545E35CB6CD25B9C CRC64;
     MHCAEAGKAL IKFNHCEKYI YSFSVPQCCP LCQQDLGSRK LEDAPVSIAN PFTNGHQEKC
     SFLLRPTQGT FLREYDGRSD LHVGITNTNG VVYNYSAHGV QRDGEGWEES ISIPLLQPNM
     YGMMEQWDKY LEDFSTSGAW LPHRYEDNHH NCYSYALTFI NCVLMAEGRQ QLDKGEFTEK
     YVVPRTRLAS KFITLYRAIR EHGFYVTDCP QQQAQPPEGG GLC