ID   MLAB_HAEIN              Reviewed;         105 AA.
AC   Q57407; O05044;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Intermembrane phospholipid transport system binding protein MlaB {ECO:0000250|UniProtKB:P64602};
GN   Name=mlaB {ECO:0000250|UniProtKB:P64602}; OrderedLocusNames=HI_1083;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Part of the ABC transporter complex MlaFEDB, which is
CC       involved in a phospholipid transport pathway that maintains lipid
CC       asymmetry in the outer membrane by retrograde trafficking of
CC       phospholipids from the outer membrane to the inner membrane. MlaB plays
CC       critical roles in both the assembly and activity of the complex. May
CC       act by modulating MlaF structure and stability.
CC       {ECO:0000250|UniProtKB:P64602}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (MlaF),
CC       two transmembrane proteins (MlaE), two cytoplasmic solute-binding
CC       proteins (MlaB) and six periplasmic solute-binding proteins (MlaD).
CC       {ECO:0000250|UniProtKB:P64602}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250|UniProtKB:P64602}.
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DR   EMBL; L42023; AAC22739.1; -; Genomic_DNA.
DR   PIR; A64166; A64166.
DR   RefSeq; NP_439240.1; NC_000907.1.
DR   RefSeq; WP_005693407.1; NC_000907.1.
DR   AlphaFoldDB; Q57407; -.
DR   SMR; Q57407; -.
DR   STRING; 71421.HI_1083; -.
DR   EnsemblBacteria; AAC22739; AAC22739; HI_1083.
DR   KEGG; hin:HI_1083; -.
DR   PATRIC; fig|71421.8.peg.1128; -.
DR   eggNOG; COG3113; Bacteria.
DR   HOGENOM; CLU_115403_13_0_6; -.
DR   OMA; QSLHWES; -.
DR   BioCyc; HINF71421:G1GJ1-1118-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.30.750.24; -; 1.
DR   InterPro; IPR002645; STAS_dom.
DR   InterPro; IPR036513; STAS_dom_sf.
DR   Pfam; PF13466; STAS_2; 1.
DR   SUPFAM; SSF52091; SSF52091; 1.
DR   PROSITE; PS50801; STAS; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Reference proteome; Transport.
FT   CHAIN           1..105
FT                   /note="Intermembrane phospholipid transport system binding
FT                   protein MlaB"
FT                   /id="PRO_0000078001"
FT   DOMAIN          4..105
FT                   /note="STAS"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00198"
SQ   SEQUENCE   105 AA;  12105 MW;  0A629D39D79FDF6A CRC64;
     MLNWDLQKNN DKITLFLFGE LSRSTLLPMW QQRGVFLSAS TLDKTIVEWN LSDLQHIDSA
     GFAALCDFLR ECQKLNKTVR LVYPPKQLLT LADLFGLSDW IANFI