位置:首页 > 蛋白库 > MLAC_HAEIN
MLAC_HAEIN
ID   MLAC_HAEIN              Reviewed;         214 AA.
AC   P45028;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 114.
DE   RecName: Full=Intermembrane phospholipid transport system binding protein MlaC {ECO:0000250|UniProtKB:P0ADV7};
DE   Flags: Precursor;
GN   Name=mlaC {ECO:0000250|UniProtKB:P0ADV7}; OrderedLocusNames=HI_1084;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
RN   [2]
RP   IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=10675023;
RX   DOI=10.1002/(sici)1522-2683(20000101)21:2<411::aid-elps411>3.0.co;2-4;
RA   Langen H., Takacs B., Evers S., Berndt P., Lahm H.W., Wipf B., Gray C.,
RA   Fountoulakis M.;
RT   "Two-dimensional map of the proteome of Haemophilus influenzae.";
RL   Electrophoresis 21:411-429(2000).
CC   -!- FUNCTION: Involved in a phospholipid transport pathway that maintains
CC       lipid asymmetry in the outer membrane by retrograde trafficking of
CC       phospholipids from the outer membrane to the inner membrane. May
CC       transfer phospholipid across the periplasmic space and deliver it to
CC       the MlaFEDB complex at the inner membrane.
CC       {ECO:0000250|UniProtKB:P0ADV7}.
CC   -!- SUBCELLULAR LOCATION: Periplasm {ECO:0000250|UniProtKB:P0ADV7}.
CC   -!- SIMILARITY: Belongs to the MlaC/ttg2D family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; L42023; AAC22740.1; -; Genomic_DNA.
DR   PIR; B64166; B64166.
DR   RefSeq; NP_439241.1; NC_000907.1.
DR   RefSeq; WP_005693408.1; NC_000907.1.
DR   AlphaFoldDB; P45028; -.
DR   SMR; P45028; -.
DR   STRING; 71421.HI_1084; -.
DR   PRIDE; P45028; -.
DR   EnsemblBacteria; AAC22740; AAC22740; HI_1084.
DR   KEGG; hin:HI_1084; -.
DR   PATRIC; fig|71421.8.peg.1129; -.
DR   eggNOG; COG2854; Bacteria.
DR   HOGENOM; CLU_094502_3_0_6; -.
DR   OMA; ISKSIMT; -.
DR   PhylomeDB; P45028; -.
DR   BioCyc; HINF71421:G1GJ1-1119-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0042597; C:periplasmic space; IEA:UniProtKB-SubCell.
DR   Gene3D; 3.10.450.710; -; 1.
DR   InterPro; IPR008869; MlaC/ttg2D.
DR   InterPro; IPR042245; Tgt2/MlaC_sf.
DR   PANTHER; PTHR36573; PTHR36573; 1.
DR   Pfam; PF05494; MlaC; 1.
DR   PIRSF; PIRSF004649; MlaC; 1.
PE   1: Evidence at protein level;
KW   Periplasm; Reference proteome; Signal.
FT   SIGNAL          1..28
FT                   /evidence="ECO:0000255"
FT   CHAIN           29..214
FT                   /note="Intermembrane phospholipid transport system binding
FT                   protein MlaC"
FT                   /id="PRO_0000013917"
SQ   SEQUENCE   214 AA;  24510 MW;  5D209A3646FBEE75 CRC64;
     MNLIQLKKWF TILTFVLTAF LVTRTAIAET SPYVLMQQAA DKLFSDIQAN QSKIKQDPNY
     LRTIVRNDLL PYVNLEYAGS KVLGSYYKST SAEQREKFFK TFGELIEQKY AQALTNYSNQ
     KIQIESEKEL GDNNFINIRV NIIQANGVAP ILLYFKWRKG NKSGEWKVYD MVGAGVSMLE
     DTIKNWVGIL NKQGIDTLIT KMQQSASQPI IFNQ
 
 
维奥蛋白资源库 - 中文蛋白资源 CopyRight © 2010-2024