ID   MLA_ANOCA               Reviewed;          13 AA.
AC   P41589;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   11-DEC-2019, entry version 48.
DE   RecName: Full=Melanotropin alpha;
DE   AltName: Full=Alpha-MSH;
OS   Anolis carolinensis (Green anole) (American chameleon).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Iguania; Dactyloidae; Anolis.
OX   NCBI_TaxID=28377;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT VAL-13.
RC   TISSUE=Pituitary;
RX   PubMed=1667689; DOI=10.1016/0196-9781(91)90204-3;
RA   Dores R.M., Lancha A., Rand-Weaver M., Jankelow L., Adamczyk D.L.;
RT   "Detection of a novel sequence change in the major form of alpha-MSH
RT   isolated from the intermediate pituitary of the reptile, Anolis
RT   carolinensis.";
RL   Peptides 12:1261-1266(1991).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the POMC family. {ECO:0000305}.
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DR   Proteomes; UP000001646; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   InterPro; IPR013531; Mcrtin_ACTH_cent.
DR   Pfam; PF00976; ACTH_domain; 1.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Hormone; Reference proteome;
KW   Secreted.
FT   PEPTIDE         1..13
FT                   /note="Melanotropin alpha"
FT                   /id="PRO_0000044291"
FT   MOD_RES         13
FT                   /note="Valine amide"
FT                   /evidence="ECO:0000269|PubMed:1667689"
SQ   SEQUENCE   13 AA;  1608 MW;  FF990A7358BB09C1 CRC64;
     SYAMEHFRWG KPV