ID   MLA_CAMDR               Reviewed;          13 AA.
AC   P61281; P01198;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=Melanotropin alpha;
DE   AltName: Full=Alpha-MSH;
OS   Camelus dromedarius (Dromedary) (Arabian camel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX   NCBI_TaxID=9838;
RN   [1]
RP   PROTEIN SEQUENCE, ACETYLATION AT SER-1, AND AMIDATION AT VAL-13.
RX   PubMed=1125179; DOI=10.1021/bi00676a011;
RA   Li C.H., Danho W.O., Chung D., Rao A.J.;
RT   "Isolation, characterization, and amino acid sequence of melanotropins from
RT   camel pituitary glands.";
RL   Biochemistry 14:947-952(1975).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- PTM: About 50% of molecules were found to be acetylated on the N-
CC       terminal serine.
CC   -!- SIMILARITY: Belongs to the POMC family. {ECO:0000305}.
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DR   PIR; A01464; MTCMAD.
DR   SMR; P61281; -.
DR   iPTMnet; P61281; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   InterPro; IPR013531; Mcrtin_ACTH_cent.
DR   Pfam; PF00976; ACTH_domain; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Amidation; Direct protein sequencing; Hormone; Secreted.
FT   PEPTIDE         1..13
FT                   /note="Melanotropin alpha"
FT                   /id="PRO_0000044292"
FT   MOD_RES         1
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000269|PubMed:1125179"
FT   MOD_RES         13
FT                   /note="Valine amide"
FT                   /evidence="ECO:0000269|PubMed:1125179"
SQ   SEQUENCE   13 AA;  1624 MW;  FF991CA958BB09C1 CRC64;
     SYSMEHFRWG KPV