ID   MLA_HORSE               Reviewed;          13 AA.
AC   P61280; P01198;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Melanotropin alpha;
DE   AltName: Full=Alpha-MSH;
OS   Equus caballus (Horse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX   NCBI_TaxID=9796;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT VAL-13.
RC   TISSUE=Pituitary;
RA   Dixon J.S., Li C.H.;
RT   "The isolation and structure of alpha-melanocyte-stimulating hormone from
RT   horse pituitaries.";
RL   J. Am. Chem. Soc. 82:4568-4572(1960).
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the POMC family. {ECO:0000305}.
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DR   PIR; A91785; MTHOAD.
DR   SMR; P61280; -.
DR   Proteomes; UP000002281; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   InterPro; IPR013531; Mcrtin_ACTH_cent.
DR   Pfam; PF00976; ACTH_domain; 1.
PE   1: Evidence at protein level;
KW   Acetylation; Amidation; Direct protein sequencing; Hormone;
KW   Reference proteome; Secreted.
FT   PEPTIDE         1..13
FT                   /note="Melanotropin alpha"
FT                   /id="PRO_0000044293"
FT   MOD_RES         1
FT                   /note="N-acetylserine"
FT                   /evidence="ECO:0000250|UniProtKB:P61281"
FT   MOD_RES         13
FT                   /note="Valine amide"
FT                   /evidence="ECO:0000269|Ref.1"
SQ   SEQUENCE   13 AA;  1624 MW;  FF991CA958BB09C1 CRC64;
     SYSMEHFRWG KPV