ID   MLB_HORSE               Reviewed;          18 AA.
AC   P01202;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 54.
DE   RecName: Full=Melanotropin beta;
DE   AltName: Full=Beta-MSH;
OS   Equus caballus (Horse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus.
OX   NCBI_TaxID=9796;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Pituitary;
RX   PubMed=13723150; DOI=10.1016/0016-6480(61)90044-2;
RA   Dixon J.S., Li C.H.;
RT   "The isolation and structure of beta-melanocyte-stimulating hormone from
RT   horse pituitary glands.";
RL   Gen. Comp. Endocrinol. 1:161-169(1961).
CC   -!- FUNCTION: MSH (melanocyte-stimulating hormone) increases the
CC       pigmentation of skin by increasing melanin production in melanocytes.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the POMC family. {ECO:0000305}.
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DR   PIR; A01467; MTHOB.
DR   AlphaFoldDB; P01202; -.
DR   STRING; 9796.ENSECAP00000013923; -.
DR   Proteomes; UP000002281; Unplaced.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR   InterPro; IPR013531; Mcrtin_ACTH_cent.
DR   Pfam; PF00976; ACTH_domain; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Hormone; Reference proteome; Secreted.
FT   PEPTIDE         1..18
FT                   /note="Melanotropin beta"
FT                   /id="PRO_0000044294"
SQ   SEQUENCE   18 AA;  2235 MW;  DA6D189914515B23 CRC64;
     DEGPYKMEHF RWGSPRKD