MLB_SCYCA
ID MLB_SCYCA Reviewed; 18 AA.
AC P01206;
DT 21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT 21-JUL-1986, sequence version 1.
DT 11-DEC-2019, entry version 44.
DE RecName: Full=Melanotropin beta;
DE AltName: Full=Beta-MSH;
OS Scyliorhinus canicula (Small-spotted catshark) (Squalus canicula).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Elasmobranchii; Galeomorphii; Galeoidea; Carcharhiniformes; Scyliorhinidae;
OC Scyliorhinus.
OX NCBI_TaxID=7830;
RN [1]
RP PROTEIN SEQUENCE.
RX PubMed=4452470; DOI=10.1016/0016-6480(74)90152-x;
RA Love R.M., Pickering B.T.;
RT "A beta-MSH in the pituitary gland of the spotted dogfish (Scyliorhinus
RT canicula): isolation and structure.";
RL Gen. Comp. Endocrinol. 24:398-404(1974).
CC -!- FUNCTION: MSH (melanocyte-stimulating hormone) increases the
CC pigmentation of skin by increasing melanin production in melanocytes.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the POMC family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR PIR; A01470; MTDFBC.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005179; F:hormone activity; IEA:UniProtKB-KW.
DR InterPro; IPR013531; Mcrtin_ACTH_cent.
DR Pfam; PF00976; ACTH_domain; 1.
PE 1: Evidence at protein level;
KW Direct protein sequencing; Hormone; Secreted.
FT PEPTIDE 1..18
FT /note="Melanotropin beta"
FT /id="PRO_0000044295"
SQ SEQUENCE 18 AA; 2195 MW; 353C93A30C314DF4 CRC64;
BZIBYKMGHF RWGAPMDK