MLC1_DROMA
ID MLC1_DROMA Reviewed; 82 AA.
AC Q24399; Q24398;
DT 01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-NOV-1996, sequence version 1.
DT 25-MAY-2022, entry version 84.
DE RecName: Full=Myosin light chain alkali;
DE Flags: Fragment;
GN Name=Mlc1;
OS Drosophila mauritiana (Fruit fly).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC Drosophilidae; Drosophila; Sophophora.
OX NCBI_TaxID=7226;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND ALTERNATIVE SPLICING.
RX PubMed=8742636; DOI=10.1093/oxfordjournals.molbev.a025608;
RA Clark A.G., Leicht B.G., Muse S.V.;
RT "Length variation and secondary structure of introns in the Mlc1 gene in
RT six species of Drosophila.";
RL Mol. Biol. Evol. 13:471-482(1996).
CC -!- SUBUNIT: Myosin is a hexamer of 2 heavy chains and 4 light chains.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=Larval-adult; Synonyms=Larval-non-IFM;
CC IsoId=Q24399-1; Sequence=Displayed;
CC Name=Indirect flight muscle; Synonyms=Pupa, Adult flight muscle;
CC IsoId=Q24399-2; Sequence=VSP_003366;
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DR EMBL; L49006; AAC37268.1; -; Genomic_DNA.
DR EMBL; L49006; AAC37269.1; -; Genomic_DNA.
DR AlphaFoldDB; Q24399; -.
DR SMR; Q24399; -.
DR FlyBase; FBgn0015105; Dmau\Mlc1.
DR GO; GO:0005859; C:muscle myosin complex; ISS:UniProtKB.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR InterPro; IPR029655; Mlc1.
DR PANTHER; PTHR23048:SF33; PTHR23048:SF33; 1.
DR SUPFAM; SSF47473; SSF47473; 1.
DR PROSITE; PS50222; EF_HAND_2; 1.
PE 4: Predicted;
KW Alternative splicing; Motor protein; Muscle protein; Myosin; Repeat.
FT CHAIN <1..82
FT /note="Myosin light chain alkali"
FT /id="PRO_0000198708"
FT DOMAIN 7..42
FT /note="EF-hand"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT VAR_SEQ 69..82
FT /note="QFVQRLMSDPVVFD -> PFLARMCERPDQLK (in isoform
FT Indirect flight muscle)"
FT /evidence="ECO:0000305"
FT /id="VSP_003366"
FT NON_TER 1
SQ SEQUENCE 82 AA; 9489 MW; BCBD4EBFFDC6743F CRC64;
KKEKEQGCYE DFIECLKLYD KEENGTMMLA ELQHALLALG ESLDDEQVET LFADCMDPED
DEGFIPYSQF VQRLMSDPVV FD