ID   MLC1_DROVI              Reviewed;         155 AA.
AC   Q24756; Q24755;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   25-MAY-2022, entry version 102.
DE   RecName: Full=Myosin light chain alkali;
GN   Name=Mlc1;
OS   Drosophila virilis (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila.
OX   NCBI_TaxID=7244;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND ALTERNATIVE SPLICING.
RC   TISSUE=Flight muscle, Head, and Larva;
RX   PubMed=8355600; DOI=10.1093/oxfordjournals.molbev.a040043;
RA   Leicht B.G., Lyckegaard E.M.S., Benedict C.M., Clark A.G.;
RT   "Conservation of alternative splicing and genomic organization of the
RT   myosin alkali light-chain (Mlc1) gene among Drosophila species.";
RL   Mol. Biol. Evol. 10:769-790(1993).
CC   -!- SUBUNIT: Myosin is a hexamer of 2 heavy chains and 4 light chains.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=2;
CC       Name=Larval-adult; Synonyms=Larval-non-IFM;
CC         IsoId=Q24756-1; Sequence=Displayed;
CC       Name=Indirect flight muscle; Synonyms=Pupa, Adult flight muscle;
CC         IsoId=Q24756-2; Sequence=VSP_003372;
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DR   EMBL; L08053; AAA28693.1; -; Genomic_DNA.
DR   EMBL; L08053; AAA28692.1; -; Genomic_DNA.
DR   RefSeq; XP_002055989.2; XM_002055953.2. [Q24756-1]
DR   RefSeq; XP_015026000.1; XM_015170514.1. [Q24756-2]
DR   AlphaFoldDB; Q24756; -.
DR   SMR; Q24756; -.
DR   STRING; 7244.FBpp0225105; -.
DR   EnsemblMetazoa; FBtr0226613; FBpp0225105; FBgn0013088. [Q24756-1]
DR   EnsemblMetazoa; FBtr0442873; FBpp0399318; FBgn0013088. [Q24756-2]
DR   GeneID; 6632300; -.
DR   KEGG; dvi:6632300; -.
DR   eggNOG; KOG0030; Eukaryota.
DR   ChiTaRS; Mlc1; fly.
DR   GO; GO:0005859; C:muscle myosin complex; ISS:UniProtKB.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   GO; GO:0007498; P:mesoderm development; IEA:EnsemblMetazoa.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR029655; Mlc1.
DR   PANTHER; PTHR23048:SF33; PTHR23048:SF33; 1.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
PE   4: Predicted;
KW   Alternative splicing; Motor protein; Muscle protein; Myosin; Repeat.
FT   CHAIN           1..155
FT                   /note="Myosin light chain alkali"
FT                   /id="PRO_0000198715"
FT   DOMAIN          7..41
FT                   /note="EF-hand 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          80..115
FT                   /note="EF-hand 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   VAR_SEQ         142..155
FT                   /note="QFIQRLMSDPVVFD -> PFLARMCDRPDAL (in isoform Indirect
FT                   flight muscle)"
FT                   /evidence="ECO:0000305"
FT                   /id="VSP_003372"
SQ   SEQUENCE   155 AA;  17617 MW;  7607373D90D0F3A5 CRC64;
     MADVPKREVE NVEFVFEVMG SPGEGIDAFD LGDALRALNL NPTLALIEKM GGTKKRNEKK
     IKLDEFLPIY SQVKKEKEQG CYEDFIECLK LYDKEENGTM LLAELQHALL ALGESLDDEQ
     VENLFADCMD PEDDEGFIPY SQFIQRLMSD PVVFD