ID   MLE1_CHERA              Reviewed;         186 AA.
AC   P82159;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 78.
DE   RecName: Full=Myosin light chain 1, skeletal muscle isoform;
DE   AltName: Full=LC-1;
DE            Short=LC1;
DE   AltName: Full=Myosin light chain alkali 1;
DE            Short=Myosin light chain A1;
OS   Chelon ramada (Thin-lipped grey mullet) (Mugil ramada).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Mugilomorphae; Mugilidae; Chelon.
OX   NCBI_TaxID=30804;
RN   [1]
RP   PROTEIN SEQUENCE.
RC   TISSUE=Fast-twitch skeletal muscle;
RX   PubMed=1939601; DOI=10.1007/bf01738591;
RA   dalla Libera L., Carpene E., Theibert J., Collins J.H.;
RT   "Fish myosin alkali light chains originate from two different genes.";
RL   J. Muscle Res. Cell Motil. 12:366-371(1991).
CC   -!- SUBUNIT: Myosin is a hexamer of 2 heavy chains and 4 light chains.
CC   -!- MISCELLANEOUS: In fish, myosin MLC1 and MLC3 appear to be produced by
CC       two different genes unlike in birds and mammals, where they are
CC       produced from a single gene by alternative splicing.
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DR   AlphaFoldDB; P82159; -.
DR   SMR; P82159; -.
DR   GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Motor protein; Muscle protein; Myosin; Repeat.
FT   CHAIN           1..186
FT                   /note="Myosin light chain 1, skeletal muscle isoform"
FT                   /id="PRO_0000198706"
FT   DOMAIN          42..77
FT                   /note="EF-hand 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          119..154
FT                   /note="EF-hand 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   REGION          1..26
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   MOD_RES         1
FT                   /note="Blocked amino end (Met)"
SQ   SEQUENCE   186 AA;  20067 MW;  57306F13CDE9E639 CRC64;
     MPKAPAKKAE PAPAPAPAPE PAPAPAAPAV DLSAVKVEFS ADQIEDYREA FGLFDRVGDN
     KVAYNQIADI MRALGQNPTN KEVSKLLGNP SADDMTNKRV EFEAFLPMLQ TIINSPNKAG
     FEDYVEGLRV FDKEGNGTVM GAELRIVLST LGEKMTEAEI DALMAGQEDE NGVVNYEAFV
     KHIMSV