ID   MLE3_CHERA              Reviewed;         148 AA.
AC   P82160;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 79.
DE   RecName: Full=Myosin light chain 3, skeletal muscle isoform;
DE   AltName: Full=LC-3;
DE            Short=LC3;
DE   AltName: Full=Myosin light chain alkali 2;
DE            Short=Myosin light chain A2;
OS   Chelon ramada (Thin-lipped grey mullet) (Mugil ramada).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata;
OC   Ovalentaria; Mugilomorphae; Mugilidae; Chelon.
OX   NCBI_TaxID=30804;
RN   [1]
RP   PROTEIN SEQUENCE, AND ACETYLATION AT THR-1.
RC   TISSUE=Fast-twitch skeletal muscle;
RX   PubMed=1939601; DOI=10.1007/bf01738591;
RA   dalla Libera L., Carpene E., Theibert J., Collins J.H.;
RT   "Fish myosin alkali light chains originate from two different genes.";
RL   J. Muscle Res. Cell Motil. 12:366-371(1991).
CC   -!- SUBUNIT: Myosin is a hexamer of 2 heavy chains and 4 light chains.
CC   -!- MISCELLANEOUS: In fish, myosin MLC1 and MLC3 appear to be produced by
CC       two different genes unlike in birds and mammals, where they are
CC       produced from a single gene by alternative splicing.
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DR   AlphaFoldDB; P82160; -.
DR   SMR; P82160; -.
DR   iPTMnet; P82160; -.
DR   GO; GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00051; EFh; 1.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR002048; EF_hand_dom.
DR   SUPFAM; SSF47473; SSF47473; 1.
DR   PROSITE; PS50222; EF_HAND_2; 2.
PE   1: Evidence at protein level;
KW   Acetylation; Direct protein sequencing; Motor protein; Muscle protein;
KW   Myosin; Repeat.
FT   CHAIN           1..148
FT                   /note="Myosin light chain 3, skeletal muscle isoform"
FT                   /id="PRO_0000198707"
FT   DOMAIN          6..41
FT                   /note="EF-hand 1"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   DOMAIN          82..117
FT                   /note="EF-hand 2"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT   MOD_RES         1
FT                   /note="N-acetylthreonine"
FT                   /evidence="ECO:0000269|PubMed:1939601"
SQ   SEQUENCE   148 AA;  16368 MW;  DA4D62C5DF7B2634 CRC64;
     TEFSADQIED FKEAFGLFDR IGDSQVAFNQ VADIMRALGQ NPTNKDVTKI LGNPSADDMA
     NKRLNFDAFL PMLKEVDALP KGTYDDYVEG LRVFDKEGNG TVMGAELRIV LSTLGEKMTE
     PEIDALMAGQ EDEGSVHYEA FVKHIMSV