MLEX_CHICK
ID MLEX_CHICK Reviewed; 185 AA.
AC P09540; Q90897;
DT 01-JUL-1989, integrated into UniProtKB/Swiss-Prot.
DT 01-JUL-1989, sequence version 1.
DT 03-AUG-2022, entry version 125.
DE RecName: Full=Myosin light chain, embryonic;
DE AltName: Full=L23;
OS Gallus gallus (Chicken).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda;
OC Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae;
OC Phasianinae; Gallus.
OX NCBI_TaxID=9031;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=3667580; DOI=10.1016/s0021-9258(18)47809-x;
RA Kawashima M., Nabeshima Y., Obinata T., Fujii-Kuriyama Y.;
RT "A common myosin light chain is expressed in chicken embryonic skeletal,
RT cardiac, and smooth muscles and in brain continuously from embryo to
RT adult.";
RL J. Biol. Chem. 262:14408-14414(1987).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC TISSUE=Liver;
RX PubMed=3225843; DOI=10.1016/0022-2836(88)90350-6;
RA Nabeshima Y., Nabeshima Y., Kawashima M., Nakamura S., Nonomura Y.,
RA Fujii-Kuriyama Y.;
RT "Isolation of the chick myosin alkali light chain gene expressed in
RT embryonic gizzard muscle and transitional expression of the light chain
RT gene family in vivo.";
RL J. Mol. Biol. 204:497-505(1988).
CC -!- SUBUNIT: Myosin is a hexamer of 2 heavy chains and 4 light chains.
CC -!- MISCELLANEOUS: Light chain 23 is expressed in chicken embryonic
CC skeletal, cardiac, smooth muscles and in brain continuously from embryo
CC to adult.
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DR EMBL; J02823; AAA48957.1; -; mRNA.
DR EMBL; X14428; CAA32588.1; -; Genomic_DNA.
DR EMBL; X14429; CAA32588.1; JOINED; Genomic_DNA.
DR PIR; S02065; MOCH4E.
DR RefSeq; NP_990810.2; NM_205479.3.
DR AlphaFoldDB; P09540; -.
DR SMR; P09540; -.
DR STRING; 9031.ENSGALP00000000815; -.
DR PaxDb; P09540; -.
DR GeneID; 396472; -.
DR KEGG; gga:396472; -.
DR CTD; 4635; -.
DR VEuPathDB; HostDB:geneid_396472; -.
DR eggNOG; KOG0030; Eukaryota.
DR PhylomeDB; P09540; -.
DR PRO; PR:P09540; -.
DR Proteomes; UP000000539; Unplaced.
DR GO; GO:0031672; C:A band; IBA:GO_Central.
DR GO; GO:0016460; C:myosin II complex; IBA:GO_Central.
DR GO; GO:0003785; F:actin monomer binding; IBA:GO_Central.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0060048; P:cardiac muscle contraction; IBA:GO_Central.
DR CDD; cd00051; EFh; 1.
DR InterPro; IPR011992; EF-hand-dom_pair.
DR InterPro; IPR002048; EF_hand_dom.
DR SUPFAM; SSF47473; SSF47473; 1.
DR PROSITE; PS50222; EF_HAND_2; 2.
PE 2: Evidence at transcript level;
KW Motor protein; Muscle protein; Myosin; Reference proteome; Repeat.
FT CHAIN 1..185
FT /note="Myosin light chain, embryonic"
FT /id="PRO_0000198702"
FT DOMAIN 39..76
FT /note="EF-hand 1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT DOMAIN 118..153
FT /note="EF-hand 2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00448"
FT DOMAIN 153..185
FT /note="EF-hand 3"
FT /evidence="ECO:0000305"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..17
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 94
FT /note="L -> M (in Ref. 2; CAA32588)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 185 AA; 20620 MW; 50F87A074F23BACF CRC64;
MPLKKPDPKK DAAKAAAAPE VPKEFTFDPK SVKIEFAAEQ IEEFKEAFSL FDRTPTGAMQ
ITYAQCGDVL RALGHNPTNA EVLKVLGKPK PEDLNTKMLD FETFLPILQH FTRNREQGTF
EDFVEGLRVF DKEGNGLVMG AELRHVLVTL GEKMTESEVE QLMAGLEDAN GCINYEAFVK
HIMSG
